Table 6 Neuraminidase inhibition assay for A(H1N1)pdm09 viruses isolated in immunocompromised patients
Virus | Type (Subtype) | Genotype | NAI resistance (IC50 fold change) | ||
|---|---|---|---|---|---|
Oseltamivir | Zanamivir | Peramivir | |||
A/Korea/S0003/2019 | A(H1N1)pdm09 | Variant (H275Y) | HRI 179.33 | NI 2.56 | HRI 117.74 |
A/Korea/S0002/2019 | Variant (H275Y) | HRI 221.58 | NI 0.44 | HRI 168.48 | |
2018–2019 isolates | A(H1N1)pdm09 | Wild | 0.1–1.2 | 0.3–0.7 | 0.1 |
A(H3N2) | Wild | 0.1–0.2 | 0.4–0.8 | 0.2–0.3 | |
B | Wild | 9–16 | 0.7–1.6 | 0.3–0.4 | |