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Table 5 HA genetic variation compared with A/Brisbane/02/2018 (H1 numbering)

From: Characterization of neuraminidase inhibitor-resistant influenza virus isolates from immunocompromised patients in the Republic of Korea

Virus

Amino acid identity with A/Brisbane/02/2018 (%)

G62Ra,b,c

N146Da,b,c

A158E a,b,c

T202I a,b,c

R240Q a,c,d

N277Db

A299Pa,b

V315Ia,b

K521b

A/Korea/S0003/2019

98.94

 

 

 

A/Korea/S0002/2019

98.59

 

Frequency (%)

84.19

17.76

0.97

19.77

99.87

29.46

84.85

85.38

3.08

  1. substitution of the amino acid indicated
  2. aBinding small ligand
  3. bviral oligomerization interfaces
  4. cantibody recognition sites
  5. dhost cell receptor binding