Genotyping of 30 kinds of cutaneous human papillomaviruses by a multiplex microfluidic loop-mediated isothermal amplification and visual detection method

Table 1 Clinical sample HPV infection rate detected by LAMP and PCR & Sequencing: This table lists the single infection rate and multiple infection rate when using the PCR & Sequencing method and the microfluidic LAMP method to detect clinical samples, respectively

	Single infection	Multiple infection	Double infection	Triple infection	Quartet infection	HPV positive	HPV negative	Total
	n(n/N)	n(n/N)	n(n/N)	n(n/N)	n(n/N)	n(n/N)	n(n/N)	N
LAMP	30 (35.3%)	55 (64.7%)	42 (49.4%)	12 (14.1%)	1 (1.2%)	85 (100%)	0 (0)	85
PCR	62 (72.9%)	0 (0)	0 (0)	0 (0)	0 (0)	62 (72.9%)	23 (27.1%)	85

LAMP represents the new HPV detection system based on LAMP and microfluidic chip. PCR represents DNA sequencing based on PCR methods
Abbreviations: HPV human papillomaviruses, LAMP Loop-mediated isothermal amplification, PCR Polymerase Chain Reaction

ISSN: 1743-422X