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Table 4 The HSV-1/2 tissue tropism and the TRFs expression in different tissues

From: Novel transcription regulatory sequences and factors of the immune evasion protein ICP47 (US12) of herpes simplex viruses

System Cell/ tissue HSV-1 HSV-2 c-Rel HNF-4 Elk-1 Pax-4 CF2-II OCT-1
Blood system CD34+ stem cell + _ H H H H H H
721 B lymphoblasts + _ H H H H M H
CD19 + B cell + _ H H H H M H
Leukemia lymphoblastic + _ M M M M L L
Bonemarrow + _ H M H H M H
Pituitariy + _ H H H H H M
Head Prefrontal Cortex + _ H H H H H H
Pineal + _ H H H H H M
Tongue + _ H M H H L M
Tonsil + _ H M M H L L
Retina + _ H H H H H M
Trigeminal ganglion + _ M H H H L L
Cerebellum + _ H H M H H M
Viscera Heart + _ H H H H H M
Lung + _ H H H H H M
Liver + _ H H H H H M
Kidney + _ M M M M H L
Smooth Muscles + _ H H H H H M
Adipocyte + _ H M M H L L
Secretory system Adrenalgland + _ M M H H L L
Pancreaticlstet + _ H H H H H M
Genital system Placenta + + H H H M H M
Fetalthyroid + + H M M M H M
Uterus + + M M M M M L
Testis + + M M M M H L
Ovary + + M M L L L M