TY - JOUR AU - Cheng, Jun-Ting AU - Wang, Ying-Ying AU - Zhu, Lin-Zhong AU - Zhang, Ying AU - Cai, Wen-Qi AU - Han, Zi-Wen AU - Zhou, Yang AU - Wang, Xian-Wang AU - Peng, Xiao-Chun AU - Xiang, Ying AU - Yang, Hui-Yu AU - Cui, Shu-Zhong AU - Ma, Zhaowu AU - Liu, Bing-Rong AU - Xin, Hong-Wu PY - 2020 DA - 2020/07/10 TI - Novel transcription regulatory sequences and factors of the immune evasion protein ICP47 (US12) of herpes simplex viruses JO - Virology Journal SP - 101 VL - 17 IS - 1 AB - Herpes simplex virus (HSV) can cause encephalitis. Its infected cell polypeptide 47 (ICP47), encoded by immediate-early gene US12, promotes immune escape. ICP47 was modified in the clinically approved oncolytic HSV (oHSV) T-Vec. However, transcription regulatory sequence (TRS) and transcription regulatory factor (TRF) of HSV US12 are seldom reported. SN - 1743-422X UR - https://doi.org/10.1186/s12985-020-01365-3 DO - 10.1186/s12985-020-01365-3 ID - Cheng2020 ER -