Promising application of monoclonal antibody against chikungunya virus E1-antigen across genotypes in immunochromatographic rapid diagnostic tests

Table 3 Evaluation of 3rd-generation CHIKV E1 detection RDT version O in clinical samples

PCR	IC RDT		Sensitivity	Specificity	OAA
PCR	(+)	(−)	Sensitivity	Specificity	OAA
(+)^a	92	8	92		96
(−)^b	0	100		100

Sensitivity: percentage of matches between results of PCR and IC RDT in PCR positive samples
Specificity: percentage of matches between results of PCR and IC RDT in PCR negative samples
OAA overall agreement
^a 99 anti-CHIKV IgM-negative samples and one anti-CHIKV IgM-positive sample
^bdengue PCR-positive samples

ISSN: 1743-422X