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Table 2 Secular trends of different HPV subtype infection rates from 2011 to 2019

From: Prevalence characteristics of cervical human papillomavirus (HPV) infection in the Zhoupu District, Shanghai City, China

HPV subtype

2011,n(%)

2012,n(%)

2013,n(%)

2014,n(%)

2015,n(%)

2016,n(%)

2017,n(%)

2018,n(%)

2019,n(%)

P value for trend

HPV16

58 (17.52)

107 (13.21)

181 (14.62)

216 (10.34)

240 (10.95)

251 (10.87)

378 (10.99)

263 (10.59)

1 (11.11)

0.002

HPV52

57 (17.22)

118 (14.57)

178 (14.38)

296 (14.18)

317 (14.46)

286 (12.38)

482 (14.01)

393 (15.83)

3 (33.33)

0.0029

HPV58

29 (8.76)

110 (13.58)

114 (9.21)

228 (10.92)

202 (9.22)

258 (11.17)

343 (9.97)

286 (11.52)

1 (11.11)

0.003

HPV81

23 (6.95)

58 (7.16)

97 (7.84)

177 (8.48)

203 (9.26)

225 (9.74)

234 (6.8)

137 (5.52)

1 (11.11)

0.0033

HPV53

21 (6.34)

58 (7.16)

75 (6.06)

139 (6.66)

164 (7.48)

181 (7.84)

243 (7.06)

199 (8.01)

0 (0)

0.0012

HPV11

21 (6.34)

39 (4.81)

64 (5.17)

77 (3.69)

82 (3.74)

67 (2.9)

112 (3.26)

80 (3.22)

0 (0)

0.0037

HPV18

19 (5.74)

40 (4.94)

54 (4.36)

79 (3.78)

96 (4.38)

77 (3.33)

133 (3.87)

105 (4.23)

0 (0)

0.0022

HPV6

17 (5.14)

44 (5.43)

52 (4.2)

105 (5.03)

105 (4.79)

104 (4.5)

118 (3.43)

91 (3.66)

0 (0)

0.002

HPV31

15 (4.53)

38 (4.69)

68 (5.49)

101 (4.84)

72 (3.28)

93 (4.03)

122 (3.55)

66 (2.66)

0 (0)

0.0022

HPV33

15 (4.53)

68 (8.4)

67 (5.41)

139 (6.66)

108 (4.93)

117 (5.06)

148 (4.3)

100 (4.03)

0 (0)

0.0019

HPV66

13 (3.93)

18 (2.22)

37 (2.99)

54 (2.59)

76 (3.47)

82 (3.55)

118 (3.43)

96 (3.87)

0 (0)

0.0047

HPV68

12 (3.63)

26 (3.21)

70 (5.65)

89 (4.26)

77 (3.51)

81 (3.51)

133 (3.87)

102 (4.11)

0 (0)

0.0031

HPV39

7 (2.11)

26 (3.21)

41 (3.31)

112 (5.36)

151 (6.89)

166 (7.19)

212 (6.16)

156 (6.28)

0 (0)

0.0076

HPV45

5 (1.51)

7 (0.86)

20 (1.62)

29 (1.39)

17 (0.78)

30 (1.3)

43 (1.25)

20 (0.81)

2 (22.22)

0.0033

HPV56

5 (1.51)

20 (2.47)

36 (2.91)

41 (1.96)

44 (2.01)

37 (1.6)

98 (2.85)

59 (2.38)

0 (0)

0.0056

HPV51

4 (1.21)

7 (0.86)

18 (1.45)

105 (5.03)

155 (7.07)

151 (6.54)

257 (7.47)

166 (6.69)

0 (0)

0.016

HPV59

4 (1.21)

10 (1.23)

24 (1.94)

31 (1.48)

33 (1.51)

38 (1.65)

53 (1.54)

45 (1.81)

0 (0)

0.0032

HPV35

3 (0.91)

11 (1.36)

12 (0.97)

31 (1.48)

20 (0.91)

20 (0.87)

44 (1.28)

32 (1.29)

0 (0)

0.0047

HPV44

2 (0.6)

2 (0.25)

14 (1.13)

26 (1.25)

19 (0.87)

28 (1.21)

69 (2.01)

47 (1.89)

0 (0)

0.0182

HPV42

1 (0.3)

2 (0.25)

14 (1.13)

9 (0.43)

10 (0.46)

10 (0.43)

62 (1.8)

29 (1.17)

0 (0)

0.0488

HPV43

0 (0)

1 (0.12)

2 (0.16)

4 (0.19)

1 (0.05)

8 (0.35)

38 (1.1)

11 (0.44)

1 (11.11)

0.0868

Total

331

810

1238

2088

2192

2310

3440

2483

9