HPV subtype | 2011,n(%) | 2012,n(%) | 2013,n(%) | 2014,n(%) | 2015,n(%) | 2016,n(%) | 2017,n(%) | 2018,n(%) | 2019,n(%) | P value for trend |
---|---|---|---|---|---|---|---|---|---|---|
HPV16 | 58 (17.52) | 107 (13.21) | 181 (14.62) | 216 (10.34) | 240 (10.95) | 251 (10.87) | 378 (10.99) | 263 (10.59) | 1 (11.11) | 0.002 |
HPV52 | 57 (17.22) | 118 (14.57) | 178 (14.38) | 296 (14.18) | 317 (14.46) | 286 (12.38) | 482 (14.01) | 393 (15.83) | 3 (33.33) | 0.0029 |
HPV58 | 29 (8.76) | 110 (13.58) | 114 (9.21) | 228 (10.92) | 202 (9.22) | 258 (11.17) | 343 (9.97) | 286 (11.52) | 1 (11.11) | 0.003 |
HPV81 | 23 (6.95) | 58 (7.16) | 97 (7.84) | 177 (8.48) | 203 (9.26) | 225 (9.74) | 234 (6.8) | 137 (5.52) | 1 (11.11) | 0.0033 |
HPV53 | 21 (6.34) | 58 (7.16) | 75 (6.06) | 139 (6.66) | 164 (7.48) | 181 (7.84) | 243 (7.06) | 199 (8.01) | 0 (0) | 0.0012 |
HPV11 | 21 (6.34) | 39 (4.81) | 64 (5.17) | 77 (3.69) | 82 (3.74) | 67 (2.9) | 112 (3.26) | 80 (3.22) | 0 (0) | 0.0037 |
HPV18 | 19 (5.74) | 40 (4.94) | 54 (4.36) | 79 (3.78) | 96 (4.38) | 77 (3.33) | 133 (3.87) | 105 (4.23) | 0 (0) | 0.0022 |
HPV6 | 17 (5.14) | 44 (5.43) | 52 (4.2) | 105 (5.03) | 105 (4.79) | 104 (4.5) | 118 (3.43) | 91 (3.66) | 0 (0) | 0.002 |
HPV31 | 15 (4.53) | 38 (4.69) | 68 (5.49) | 101 (4.84) | 72 (3.28) | 93 (4.03) | 122 (3.55) | 66 (2.66) | 0 (0) | 0.0022 |
HPV33 | 15 (4.53) | 68 (8.4) | 67 (5.41) | 139 (6.66) | 108 (4.93) | 117 (5.06) | 148 (4.3) | 100 (4.03) | 0 (0) | 0.0019 |
HPV66 | 13 (3.93) | 18 (2.22) | 37 (2.99) | 54 (2.59) | 76 (3.47) | 82 (3.55) | 118 (3.43) | 96 (3.87) | 0 (0) | 0.0047 |
HPV68 | 12 (3.63) | 26 (3.21) | 70 (5.65) | 89 (4.26) | 77 (3.51) | 81 (3.51) | 133 (3.87) | 102 (4.11) | 0 (0) | 0.0031 |
HPV39 | 7 (2.11) | 26 (3.21) | 41 (3.31) | 112 (5.36) | 151 (6.89) | 166 (7.19) | 212 (6.16) | 156 (6.28) | 0 (0) | 0.0076 |
HPV45 | 5 (1.51) | 7 (0.86) | 20 (1.62) | 29 (1.39) | 17 (0.78) | 30 (1.3) | 43 (1.25) | 20 (0.81) | 2 (22.22) | 0.0033 |
HPV56 | 5 (1.51) | 20 (2.47) | 36 (2.91) | 41 (1.96) | 44 (2.01) | 37 (1.6) | 98 (2.85) | 59 (2.38) | 0 (0) | 0.0056 |
HPV51 | 4 (1.21) | 7 (0.86) | 18 (1.45) | 105 (5.03) | 155 (7.07) | 151 (6.54) | 257 (7.47) | 166 (6.69) | 0 (0) | 0.016 |
HPV59 | 4 (1.21) | 10 (1.23) | 24 (1.94) | 31 (1.48) | 33 (1.51) | 38 (1.65) | 53 (1.54) | 45 (1.81) | 0 (0) | 0.0032 |
HPV35 | 3 (0.91) | 11 (1.36) | 12 (0.97) | 31 (1.48) | 20 (0.91) | 20 (0.87) | 44 (1.28) | 32 (1.29) | 0 (0) | 0.0047 |
HPV44 | 2 (0.6) | 2 (0.25) | 14 (1.13) | 26 (1.25) | 19 (0.87) | 28 (1.21) | 69 (2.01) | 47 (1.89) | 0 (0) | 0.0182 |
HPV42 | 1 (0.3) | 2 (0.25) | 14 (1.13) | 9 (0.43) | 10 (0.46) | 10 (0.43) | 62 (1.8) | 29 (1.17) | 0 (0) | 0.0488 |
HPV43 | 0 (0) | 1 (0.12) | 2 (0.16) | 4 (0.19) | 1 (0.05) | 8 (0.35) | 38 (1.1) | 11 (0.44) | 1 (11.11) | 0.0868 |
Total | 331 | 810 | 1238 | 2088 | 2192 | 2310 | 3440 | 2483 | 9 |