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Table 4 Incidence of amino acid mutation/ deletion between HBsAg+/HBsAb+ group (Group I) and HBsAg+/HBsAb- group (Group II)

From: Complete genome analysis of hepatitis B virus in Qinghai-Tibet plateau: the geographical distribution, genetic diversity, and co-existence of HBsAg and anti-HBs antibodies

Section of PreS & HBsAg Number of substitutions per 100 amino acid residues
Group I Group II χ2 P value
PreS1(aa1–118) 0.44 0.26 1.836 0.18
PreS2(aa1–54) 1.92 2 0.190 0.89
PreS deletiona 11.11 0.64 11.801 < 0.001
S protein Full-length of S protein (aa1–226) 1.03 0.31 21.19 < 0.001
N-terminal (aa1–99) 1.08 0.21 25.6 < 0.001
MHR (aa100–169) 0.85 0.17 17.6 < 0.001
a determinant (aa124 ~ 147) 1.54 0.06 30.1 < 0.001
First loop (aa124–137) 1.59 0.10 20.954 < 0.001
Second loop (aa139–147) 1.06 0.00 20.804 < 0.001
C-terminal (aa170 ~ 226) 1.54 0.06 30.1 < 0.001
  1. aPreS deletion incidence was calculated by number of deletions per 100 samples
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