Fig. 5

Transcription factors prediction on LCR. (a): transcription factors prediction of HPV16. (b): transcription factors prediction of HPV18. (c): transcription factors prediction of HPV58. The JASPAR database was used to investigate the potential binding sites within HPV-LCR. The yellow strips represent sequence of LCR.: Bold black line marked boundary positions of LCR and initiation sites of genome.: Red line marked variants sites which may effect binding sites of transcription factors.: The block with dash line present the insertion we found in HPV58