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Fig. 2 | Virology Journal

Fig. 2

From: Longitudinal transcriptomic characterization of viral genes in HSV-1 infected tree shrew trigeminal ganglia

Fig. 2

Comparison of viral gene transcription activity between mouse and tree shrew. a Heatmaps reflecting expression intensity of viral genes which were differentially expressed between infected samples and mock controls. Genes with a log2 fold change > 1 and adjusted P value < 0.01 were considered differentially expressed and were displayed in the heat map by red color. White areas indicate viral genes that below the DEGs threshold. The viral genes of different phases are distinguished by boxes and different colors on the Y-axis. IE: immediate-early. log2FC: log2 fold change. b Venn diagram indicating shared viral DEGs between infected mouse and tree shrew samples. c Functional enrichment analysis for 22 selected viral genes which are below the DEGs threshold in tree shrews. The genes annotation information used in this analysis are shown in supplemental Table 1. d Relative quantitation of selected viral transcripts based on the RT-qPCR validation using 5dpi RNA samples. Data are represented as mean ± SD

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