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Fig. 7 | Virology Journal

Fig. 7

From: Pulmonary endothelium-derived PD-L1 induced by the H9N2 avian influenza virus inhibits the immune response of T cells

Fig. 7

Effect of H9N2 virus-induced PD-L1 on the proliferation of T cells. RPMECs were treated with the H9N2 virus (Virus), viral particles (Particle) or the H9N2 virus plus a PD-L1 antibody (Antibody), and then the activatedT cells were added to endothelial cells for 8 h in vitro. Migrated T cells in the bottom chamber were collected for the MTT assay. The MTT results showed the proliferation rate of T cells that migrated across RPMECs. a The proliferation rate of the activated T cells in vitro. b The proliferation rate of T cells isolated from H9N2 virus-infected rats. * Statistical analysis of T cell proliferation post treated with the H9N2 virus,or the inactivated H9N2 viral particles or the H9N2 virus+ PD-L1 antibody (*P < 0.05, **P < 0.01)

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Virology Journal

ISSN: 1743-422X