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Fig. 4 | Virology Journal

Fig. 4

From: Immunization with a fusion protein vaccine candidate generated from truncated peptides of human enterovirus 71 protects mice from lethal enterovirus 71 infections

Fig. 4

Protective effects of active immunization on mice against EV71 infection. a Clinical scores of mice immunized with 10 μg fusion protein-containing vaccine candidate upon sub-lethal EV71 infection (n = 12). Clinical scores were analyzed using Milcoxon test. b Viral RNA copies in skeletal muscle of EV71-infected mice were detected via quantitative reverse transcription polymerase chain reaction analysis (n = 6). The data represent the mean ± SD values of two independent immunization experiments. *p < 0.05, ** p < 0.001

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