Skip to main content
Fig. 5 | Virology Journal

Fig. 5

From: Disulfide isomerase ERp57 improves the stability and immunogenicity of H3N2 influenza virus hemagglutinin

Fig. 5

H3 HA/ERp57 elicited significantly higher HA-specific antibodies than H3 HA. H1N1, H3N2, and H9N2 influenza viruses were purified and inactivated as antigens for assay. BALB/c mice (n = 5) were immunized twice with H3 HA or H3 HA/ERp57 or PBS as control. a The HI titer against homologous (H3N2) and heterologous (H1N1 or H9N2) antigens. The collected serum samples were assayed for HI titers following the conventional HI assay. ND denotes HI antibody not detectable. b The HA-specific antibodies against homologous (H3N2) and heterologous (H1N1 or H9N2) antigens. * represents p < 0.05, ** represents p < 0.01, **** represents p < 0.0001

Back to article page