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Table 2 Ratio for the effect of CsA on HIV infectivity

From: Characterization of HIV-1 uncoating in human microglial cell lines

Time (hr)

CsA/EtOH ratio

HIV-GFP

N74D

0

0.72

0.76

0.25

0.63

0.65

0.5

0.68

0.70

0.75

0.70

0.69

1

0.68

0.68

2

0.64

0.68

3

0.70

0.65

4

0.69

0.75

5

0.72

0.73

  1. The magnitude of the effect of CsA was determined by calculating a ratio of infectivity (%GPP positive cells with CsA treatment/%GPP positive cells in EtOH carrier control) for each time point examined for HIV-GFP and N74D virus. In general, the CsA containing reactions exhibited 63–75% of the infected cells in the corresponding ethanol control