Fig. 4

Multi-cycle growth curves of assembled viruses featuring different NS RNA structures. MDCK (a), Vero (b), and A549 (c) cells were infected at moi = 0.001 TCID₅₀/cell. The infectious activity of virus progeny was measured at the indicated time points by TCID₅₀ assay. Error bars represent mean ± SD (n = 3)