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Fig. 5 | Virology Journal

Fig. 5

From: EOS, an Ikaros family zinc finger transcription factor, interacts with the HTLV-1 oncoprotein Tax and is downregulated in peripheral blood mononuclear cells of HTLV-1-infected individuals, irrespective of clinical statuses

Fig. 5

Comparison of EOS mRNA levels with tax and HBZ mRNA levels as well as with HTLV-1 PVL among HTLV-1 infected individuals with different clinical statuses. Positive correlations were observed between both EOS mRNA load and PVL, and EOS and HBZ mRNA load in HAM/TSP patients, but not in patients with other clinical statuses (first row, left and middle panels). In ACs, the EOS mRNA level in PBMCs did not correlate with HTLV-1 PVL or Tax and HBZ mRNA expression (second row). There is an inverse correlation between EOS mRNA load and PVL in ATL patients, but not in patients with other clinical statuses (third row, left panel)

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Virology Journal

ISSN: 1743-422X