Table 5 The performance of p16, p16/Ki-67 and p16/Ki-67/HPV test to predict the behavior of CIN1 and CIN2 lesions
Initial diagnosis | Number | Interval month | Return visit result | Prediction result | Coincidence rate (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Progression | Persistence | Regression | Positivity | Negativity | No HPV infection | HPV-16 and/or 58 infection | Other HPVs infection | Total | |||
CIN1 | 21 | 4.3 ± 3.37 | 3 | 5 | 13 | 11 | 10 | 1/1 (100) | 8/15 (53.3) | 3/5 (60) | 12/21 (57.1) |
CIN2 | 27 | 3.02 ± 1.44 | 6 | 6 | 15 | 21 | 6 | 1/4 (25) | 9/12 (75) | 6/11 (54.5) | 16/27 (59.3) |
Total | 48 | 3.58 ± 2.53 | 9 | 11 | 28 | 32 | 16 | 2/5 (40) | 17/27 (63) | 8/16 (50) | 27/48 (56.3) |