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Table 5 The performance of p16, p16/Ki-67 and p16/Ki-67/HPV test to predict the behavior of CIN1 and CIN2 lesions

From: Combining HPV DNA load with p16/Ki-67 staining to detect cervical precancerous lesions and predict the progression of CIN1–2 lesions

Initial diagnosis Number Interval month Return visit result Prediction result Coincidence rate (%)
Progression Persistence Regression Positivity Negativity No HPV infection HPV-16 and/or 58 infection Other HPVs infection Total
CIN1 21 4.3 ± 3.37 3 5 13 11 10 1/1 (100) 8/15 (53.3) 3/5 (60) 12/21 (57.1)
CIN2 27 3.02 ± 1.44 6 6 15 21 6 1/4 (25) 9/12 (75) 6/11 (54.5) 16/27 (59.3)
Total 48 3.58 ± 2.53 9 11 28 32 16 2/5 (40) 17/27 (63) 8/16 (50) 27/48 (56.3)