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Table 3 Correlation analysis between HPV DNA load and lesion severity, p16 score, Ki-67 score

From: Combining HPV DNA load with p16/Ki-67 staining to detect cervical precancerous lesions and predict the progression of CIN1–2 lesions

Type

Lesion severity (P value)

p16 score (P value)

Ki-67 score (P value)

HPV-16

0.203* (0.016)

0.168* (0.047)

0.035 (0.679)

HPV-18

−0.168 (0.533)

−0.151 (0.578)

−0.143 (0.598)

HPV-31

0.280 (0.293)

0.478 (0.061)

0.433 (0.094)

HPV-33

−0.002 (0.994)

0.367 (0.102)

−0.272 (0.232)

HPV-35

−0.437 (0.179)

− 0.369 (0.264)

− 0.491 (0.125)

HPV-39

−0.108 (0.724)

− 0.262 (0.388)

−0.21 (0.491)

HPV-45

0.332 (0.784)

0.704 (0.503)

0.869 (0.33)

HPV-51

−0.257 (0.336)

−0.295 (0.268)

− 0.087 (0.749)

HPV-52

0.012 (0.931)

−0.016 (0.907)

0.101 (0.457)

HPV-56

0.031 (0.932)

−0.021 (0.955)

−0.012 (0.975)

HPV-58

0.364** (0.004)

0.180 (0.165)

0.106 (0.416)

HPV-59

−0.241 (0.566)

−0.291 (0.485)

− 0.171 (0.686)

HPV-68

−0.437 (0.179)

− 0.369 (0.264)

−0.491 (0.125)

Total

0.111 (0.068)

0.147* (0.015)

0.062 (0.307)

  1. * at the P < 0.05 level
  2. ** at the P < 0.01 level