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Table 3 Correlation analysis between HPV DNA load and lesion severity, p16 score, Ki-67 score

From: Combining HPV DNA load with p16/Ki-67 staining to detect cervical precancerous lesions and predict the progression of CIN1–2 lesions

Type Lesion severity (P value) p16 score (P value) Ki-67 score (P value)
HPV-16 0.203* (0.016) 0.168* (0.047) 0.035 (0.679)
HPV-18 −0.168 (0.533) −0.151 (0.578) −0.143 (0.598)
HPV-31 0.280 (0.293) 0.478 (0.061) 0.433 (0.094)
HPV-33 −0.002 (0.994) 0.367 (0.102) −0.272 (0.232)
HPV-35 −0.437 (0.179) − 0.369 (0.264) − 0.491 (0.125)
HPV-39 −0.108 (0.724) − 0.262 (0.388) −0.21 (0.491)
HPV-45 0.332 (0.784) 0.704 (0.503) 0.869 (0.33)
HPV-51 −0.257 (0.336) −0.295 (0.268) − 0.087 (0.749)
HPV-52 0.012 (0.931) −0.016 (0.907) 0.101 (0.457)
HPV-56 0.031 (0.932) −0.021 (0.955) −0.012 (0.975)
HPV-58 0.364** (0.004) 0.180 (0.165) 0.106 (0.416)
HPV-59 −0.241 (0.566) −0.291 (0.485) − 0.171 (0.686)
HPV-68 −0.437 (0.179) − 0.369 (0.264) −0.491 (0.125)
Total 0.111 (0.068) 0.147* (0.015) 0.062 (0.307)
  1. * at the P < 0.05 level
  2. ** at the P < 0.01 level