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Fig. 1 | Virology Journal

Fig. 1

From: Combining HPV DNA load with p16/Ki-67 staining to detect cervical precancerous lesions and predict the progression of CIN1–2 lesions

Fig. 1

Sensitivity and specificity of the p16/Ki-67/HPV load co-test to detect CIN in a histopathologically diagnosed population. (a, d & g) The assessment of 13 genotypes of HR-HPV DNA load were combined with p16 and Ki-67 tests to detect CIN1+, CIN2+ and CIN3+ lesions in the 350 cases, respectively; (b, e, & h) HPV-16 and/or 58 DNA load assessments were combined with p16 and Ki-67 tests to detect CIN1+, CIN2+ and CIN3+ lesions in the 186 cases with HPV-16 and/or 58 infection, respectively; (c, f, & i) Non-16 or 58-HPV DNA load assessments were combined with the p16 and Ki-67 tests to detect CIN1+, CIN2+ and CIN3+ lesions in the 85 cases with non-16 or 58 HPVs infection, respectively

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Virology Journal

ISSN: 1743-422X