Tumor necrosis factor-α-induced protein 8-like 2 mRNA in peripheral blood mononuclear cells is associated with the disease progression of chronic hepatitis B virus infection

Table 2 Relationship between TIPE2 expression in PBMCs and clinical pathological parameters of HCC patients

Parameter	Total number	Expression of TIPE2	P value
Sex
Male	35	0.45 [0.23,0.56]	0.08
Female	6	0.59 [0.46,0.75]
Age (years)
≤ 60	23	0.45 [0.31,0.67]	0.713
>60	18	0.45 [0.22,0.53]
HBeAg
Negative	24	0.43 [0.3,0.61]	0.968
Positive	17	0.45 [0.25,0.62]
Cirrhosis
Absent	20	0.45 [0.30,0.52]	0.327
Present	21	0.45 [0.27, 0.72]
AFP ng/ml
≤ 400	23	0.48 [0.34,0.67]	0.134
>400	18	0.38 [0.22,0.56]
Venous invasion
Negative	19	0.52 [0.45, 0.75]	0.002
Positive	22	0.35 [0.19,0.52]
Primary tumor number
Single	29	0.45 [0.23, 0.64]	0.703
Multiple	12	0.42 [0.32,0.54]
Tumor size
≤ 5 cm	18	0.56 [0.35,0.75]	0.007
>5 cm	23	0.39 [0.23,0.47]
TNM staging
I/II	27	0.54 [0.45,0.76]	0.001
III/IV	14	0.35 [0.23,0.52]

Quantitative variables are expressed as the median (25th percentile; 75th percentile)
HBeAg Hepatitis B e antigen, AFP α-fetoprotein, TNM Tumor node metastasis

ISSN: 1743-422X