Fig. 4
From: Construction and characterization of an infectious cDNA clone of coxsackievirus A 10
The virulence evaluation of the rescued CA10 viruses. Seven groups of one-day-old ICR mice were challenged with 10-fold serial dilution of recovered CA10 (107 TCID50~101 TCID50) via intracerebral routes. a Survival curve of the neonatal mice. b Average body weight of the neonatal mice. c Health scores of the neonatal mice. The survival rates were evaluated by the Mantel-Cox log-rank test. The clinical scores and the body weight were compared using Dunn’s multiple-comparison test. ****:P < 0.0001, ***:P < 0.001, **:P < 0.01