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Fig. 1 | Virology Journal

Fig. 1

From: Highly pathogenic avian influenza H7N9 viruses with reduced susceptibility to neuraminidase inhibitors showed comparable replication capacity to their sensitive counterparts

Fig. 1

Replication kinetics of recombinant viruses in MDCK cells. Cells were inoculated with the recombinant viruses at 37 °C, and culture supernatants were harvested at 0, 18, 24, 48, 72 and 96 h post-inoculation. Virus titers were determined on MDCK cells. Growth curve of the rg006-NA292R(119E, 246A, 274H) in MDCK cells was in red, round; rg006-NA119V viruses were in blue, square (a); rg006-NA246T virus in purple, square (b); rg006-NA274Y virus in brown square (c); rg006-NA292Kviruses in green, square (d). Each data point represents the log10 mean ± SD TCID50/mL from at least two independent tests. *P < 0.05

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