TY - JOUR AU - Keshavarz, Mohsen AU - Namdari, Haideh AU - Farahmand, Mohammad AU - Mehrbod, Parvaneh AU - Mokhtari-Azad, Talat AU - Rezaei, Farhad PY - 2019 DA - 2019/06/13 TI - Association of polymorphisms in inflammatory cytokines encoding genes with severe cases of influenza A/H1N1 and B in an Iranian population JO - Virology Journal SP - 79 VL - 16 IS - 1 AB - The increased levels of blood cytokines is the main immunopathological process that were attributed to severe clinical outcomes in cases of influenza A, influenza B and people with influenza-like illness (ILI). Functional genetic polymorphisms caused by single nucleotide polymorphisms (SNPs) in inflammatory cytokines genes can influence their functions either qualitatively or quantitatively, which is associated with the possibility of severe influenza infections. The aim of the present case-control study was to investigate the association of polymorphisms in inflammatory cytokines genes with influenza patients and ILI group in an Iranian population. SN - 1743-422X UR - https://doi.org/10.1186/s12985-019-1187-8 DO - 10.1186/s12985-019-1187-8 ID - Keshavarz2019 ER -