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Fig. 2 | Virology Journal

Fig. 2

From: The interaction of hepatitis B virus with the ubiquitin proteasome system in viral replication and associated pathogenesis

Fig. 2

The mechanisms related to the UPS in the pathogenesis mediated by HBx. HBx could promote the development of HCC through promoting or inhibiting the functions of different components of the UPS and the ubiquitination of proteins mediated by the UPS to regulate several biological processes and molecular functions, including proliferation, apoptosis, angiogenesis, EMT, invasion, cell cycle, stem-like properties, and insulin signaling. EMT: epithelial-mesenchymal transition

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