TY - JOUR AU - Nelson, N. P. AU - Easterbrook, P. J. AU - McMahon, B. J. PY - 2016 DA - 2016// TI - Epidemiology of hepatitis B virus infection and impact of vaccination on disease JO - Clin Liver Dis. VL - 20 UR - https://doi.org/10.1016/j.cld.2016.06.006 DO - 10.1016/j.cld.2016.06.006 ID - Nelson2016 ER - TY - JOUR AU - Ganem, D. AU - Prince, A. M. PY - 2004 DA - 2004// TI - Hepatitis B virus infection--natural history and clinical consequences JO - N Engl J Med VL - 350 UR - https://doi.org/10.1056/NEJMra031087 DO - 10.1056/NEJMra031087 ID - Ganem2004 ER - TY - JOUR AU - Wu, C. C. AU - Chen, Y. S. AU - Cao, L. AU - Chen, X. W. AU - Lu, M. J. PY - 2018 DA - 2018// TI - Hepatitis B virus infection: defective surface antigen expression and pathogenesis JO - World J Gastroenterol VL - 24 UR - https://doi.org/10.3748/wjg.v24.i31.3488 DO - 10.3748/wjg.v24.i31.3488 ID - Wu2018 ER - TY - STD TI - Yan H, Zhong G, Xu G, He W, Jing Z, Gao Z, Huang Y, Qi Y, Peng B, Wang H, et al. Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus. Elife. 2012;3. ID - ref4 ER - TY - JOUR AU - Seeger, C. AU - Mason, W. S. PY - 2000 DA - 2000// TI - Hepatitis B virus biology JO - Microbiol Mol Biol Rev VL - 64 UR - https://doi.org/10.1128/MMBR.64.1.51-68.2000 DO - 10.1128/MMBR.64.1.51-68.2000 ID - Seeger2000 ER - TY - JOUR AU - Block, T. M. AU - Guo, H. AU - Guo, J. T. PY - 2007 DA - 2007// TI - Molecular virology of hepatitis B virus for clinicians JO - Clin Liver Dis VL - 11 UR - https://doi.org/10.1016/j.cld.2007.08.002 DO - 10.1016/j.cld.2007.08.002 ID - Block2007 ER - TY - JOUR AU - Sekiba, K. AU - Otsuka, M. AU - Ohno, M. AU - Yamagami, M. AU - Kishikawa, T. AU - Suzuki, T. AU - Ishibashi, R. AU - Seimiya, T. AU - Tanaka, E. AU - Koike, K. PY - 2018 DA - 2018// TI - Hepatitis B virus pathogenesis: fresh insights into hepatitis B virus RNA JO - World J Gastroenterol VL - 24 UR - https://doi.org/10.3748/wjg.v24.i21.2261 DO - 10.3748/wjg.v24.i21.2261 ID - Sekiba2018 ER - TY - JOUR AU - Tan, G. AU - Song, H. AU - Xu, F. AU - Cheng, G. PY - 2018 DA - 2018// TI - When hepatitis B virus meets interferons JO - Front Microbiol VL - 9 UR - https://doi.org/10.3389/fmicb.2018.01611 DO - 10.3389/fmicb.2018.01611 ID - Tan2018 ER - TY - JOUR AU - Hong, X. AU - Kim, E. S. AU - Guo, H. PY - 2017 DA - 2017// TI - Epigenetic regulation of hepatitis B virus covalently closed circular DNA. Implications for epigenetic therapy against chronic hepatitis B JO - Hepatology. VL - 66 UR - https://doi.org/10.1002/hep.29479 DO - 10.1002/hep.29479 ID - Hong2017 ER - TY - JOUR AU - Quasdorff, M. AU - Protzer, U. PY - 2010 DA - 2010// TI - Control of hepatitis B virus at the level of transcription JO - J Viral Hepat VL - 17 UR - https://doi.org/10.1111/j.1365-2893.2010.01315.x DO - 10.1111/j.1365-2893.2010.01315.x ID - Quasdorff2010 ER - TY - STD TI - Ortega-Prieto AM, Dorner M. Immune evasion strategies during chronic hepatitis B and C virus infection. Vaccines (Basel). 2017;5. ID - ref11 ER - TY - JOUR AU - Levrero, M. AU - Zucman-Rossi, J. PY - 2016 DA - 2016// TI - Mechanisms of HBV-induced hepatocellular carcinoma JO - J Hepatol VL - 64 UR - https://doi.org/10.1016/j.jhep.2016.02.021 DO - 10.1016/j.jhep.2016.02.021 ID - Levrero2016 ER - TY - JOUR AU - Seissler, T. a. n. j. a. AU - Marquet, R. o. l. a. n. d. AU - Paillart, J. e. a. n. -. C. h. r. i. s. t. o. p. h. e. PY - 2017 DA - 2017// TI - Hijacking of the Ubiquitin/Proteasome Pathway by the HIV Auxiliary Proteins JO - Viruses VL - 9 UR - https://doi.org/10.3390/v9110322 DO - 10.3390/v9110322 ID - Seissler2017 ER - TY - JOUR AU - Eletr, Z. M. AU - Wilkinson, K. D. PY - 2014 DA - 2014// TI - Regulation of proteolysis by human deubiquitinating enzymes JO - Biochim Biophys Acta VL - 1843 UR - https://doi.org/10.1016/j.bbamcr.2013.06.027 DO - 10.1016/j.bbamcr.2013.06.027 ID - Eletr2014 ER - TY - JOUR AU - Luo, H. PY - 2016 DA - 2016// TI - Interplay between the virus and the ubiquitin-proteasome system: molecular mechanism of viral pathogenesis JO - Curr Opin Virol VL - 17 UR - https://doi.org/10.1016/j.coviro.2015.09.005 DO - 10.1016/j.coviro.2015.09.005 ID - Luo2016 ER - TY - JOUR AU - Tang, Q. AU - Wu, P. AU - Chen, H. AU - Li, G. PY - 2018 DA - 2018// TI - Pleiotropic roles of the ubiquitin-proteasome system during viral propagation JO - Life Sci VL - 207 UR - https://doi.org/10.1016/j.lfs.2018.06.014 DO - 10.1016/j.lfs.2018.06.014 ID - Tang2018 ER - TY - JOUR AU - Blanchette, P. AU - Branton, P. E. PY - 2009 DA - 2009// TI - Manipulation of the ubiquitin-proteasome pathway by small DNA tumor viruses JO - Virology. VL - 384 UR - https://doi.org/10.1016/j.virol.2008.10.005 DO - 10.1016/j.virol.2008.10.005 ID - Blanchette2009 ER - TY - JOUR AU - Qian, G. AU - Jin, F. AU - Chang, L. AU - Yang, Y. AU - Peng, H. AU - Duan, C. PY - 2012 DA - 2012// TI - NIRF, a novel ubiquitin ligase, interacts with hepatitis B virus core protein and promotes its degradation JO - Biotechnol Lett VL - 34 UR - https://doi.org/10.1007/s10529-011-0751-0 DO - 10.1007/s10529-011-0751-0 ID - Qian2012 ER - TY - JOUR AU - Braun, S. AU - Zajakina, A. AU - Aleksejeva, J. AU - Sharipo, A. AU - Bruvere, R. AU - Ose, V. AU - Pumpens, P. AU - Garoff, H. AU - Meisel, H. AU - Kozlovska, T. PY - 2007 DA - 2007// TI - Proteasomal degradation of core protein variants from chronic hepatitis B patients JO - J Med Virol VL - 79 UR - https://doi.org/10.1002/jmv.20939 DO - 10.1002/jmv.20939 ID - Braun2007 ER - TY - JOUR AU - Wang, Z. AU - Ni, J. AU - Li, J. AU - Shi, B. AU - Xu, Y. AU - Yuan, Z. PY - 2011 DA - 2011// TI - Inhibition of hepatitis B virus replication by cIAP2 involves accelerating the ubiquitin-proteasome-mediated destruction of polymerase JO - J Virol VL - 85 UR - https://doi.org/10.1128/JVI.00879-11 DO - 10.1128/JVI.00879-11 ID - Wang2011 ER - TY - JOUR AU - Simsek, E. AU - Mehta, A. AU - Zhou, T. AU - Dwek, R. A. AU - Block, T. PY - 2005 DA - 2005// TI - Hepatitis B virus large and middle glycoproteins are degraded by a proteasome pathway in glucosidase-inhibited cells but not in cells with functional glucosidase enzyme JO - J Virol VL - 79 UR - https://doi.org/10.1128/JVI.79.20.12914-12920.2005 DO - 10.1128/JVI.79.20.12914-12920.2005 ID - Simsek2005 ER - TY - JOUR AU - Yeom, S. AU - Kim, S. S. AU - Jeong, H. AU - Jang, K. L. PY - 2017 DA - 2017// TI - Hepatitis B virus X protein activates E3 ubiquitin ligase Siah-1 to control virus propagation via a negative feedback loop JO - J Gen Virol. VL - 98 UR - https://doi.org/10.1099/jgv.0.000856 DO - 10.1099/jgv.0.000856 ID - Yeom2017 ER - TY - JOUR AU - Kim, J. H. AU - Sohn, S. Y. AU - Benedict Yen, T. S. AU - Ahn, B. Y. PY - 2008 DA - 2008// TI - Ubiquitin-dependent and -independent proteasomal degradation of hepatitis B virus X protein JO - Biochem Biophys Res Commun VL - 366 UR - https://doi.org/10.1016/j.bbrc.2007.12.070 DO - 10.1016/j.bbrc.2007.12.070 ID - Kim2008 ER - TY - JOUR AU - Bouchard, M. J. AU - Schneider, R. J. PY - 2004 DA - 2004// TI - The enigmatic X gene of hepatitis B virus JO - J Virol VL - 78 UR - https://doi.org/10.1128/JVI.78.23.12725-12734.2004 DO - 10.1128/JVI.78.23.12725-12734.2004 ID - Bouchard2004 ER - TY - JOUR AU - Iwamoto, M. AU - Watashi, K. AU - Tsukuda, S. AU - Aly, H. H. AU - Fukasawa, M. AU - Fujimoto, A. AU - Suzuki, R. AU - Aizaki, H. AU - Ito, T. AU - Koiwai, O. PY - 2014 DA - 2014// TI - Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP JO - Biochem Biophys Res Commun VL - 443 UR - https://doi.org/10.1016/j.bbrc.2013.12.052 DO - 10.1016/j.bbrc.2013.12.052 ID - Iwamoto2014 ER - TY - JOUR AU - Sun, Y. AU - Qi, Y. AU - Peng, B. AU - Li, W. PY - 2017 DA - 2017// TI - NTCP-reconstituted in vitro HBV infection system JO - Methods Mol Biol VL - 1540 UR - https://doi.org/10.1007/978-1-4939-6700-1_1 DO - 10.1007/978-1-4939-6700-1_1 ID - Sun2017 ER - TY - JOUR AU - Murphy, C. M. AU - Xu, Y. AU - Li, F. AU - Nio, K. AU - Reszka-Blanco, N. AU - Li, X. AU - Wu, Y. AU - Yu, Y. AU - Xiong, Y. AU - Su, L. PY - 2016 DA - 2016// TI - Hepatitis B virus X protein promotes degradation of SMC5/6 to enhance HBV replication JO - Cell Rep VL - 16 UR - https://doi.org/10.1016/j.celrep.2016.08.026 DO - 10.1016/j.celrep.2016.08.026 ID - Murphy2016 ER - TY - JOUR AU - Ko, C. AU - Chakraborty, A. AU - Chou, W. M. AU - Hasreiter, J. AU - Wettengel, J. M. AU - Stadler, D. AU - Bester, R. AU - Asen, T. AU - Zhang, K. AU - Wisskirchen, K. PY - 2018 DA - 2018// TI - Hepatitis B virus genome recycling and de novo secondary infection events maintain stable cccDNA levels JO - J Hepatol VL - 69 UR - https://doi.org/10.1016/j.jhep.2018.08.012 DO - 10.1016/j.jhep.2018.08.012 ID - Ko2018 ER - TY - JOUR AU - Hu, Z. AU - Zhang, Z. AU - Doo, E. AU - Coux, O. AU - Goldberg, A. L. AU - Liang, T. J. PY - 1999 DA - 1999// TI - Hepatitis B virus X protein is both a substrate and a potential inhibitor of the proteasome complex JO - J Virol VL - 73 ID - Hu1999 ER - TY - JOUR AU - Schek, N. AU - Bartenschlager, R. AU - Kuhn, C. AU - Schaller, H. PY - 1991 DA - 1991// TI - Phosphorylation and rapid turnover of hepatitis B virus X-protein expressed in HepG2 cells from a recombinant vaccinia virus JO - Oncogene. VL - 6 ID - Schek1991 ER - TY - JOUR AU - Xian, L. AU - Zhao, J. AU - Wang, J. AU - Fang, Z. AU - Peng, B. AU - Wang, W. AU - Ji, X. AU - Yu, L. PY - 2010 DA - 2010// TI - p53 promotes proteasome-dependent degradation of oncogenic protein HBx by transcription of MDM2 JO - Mol Biol Rep VL - 37 UR - https://doi.org/10.1007/s11033-009-9855-1 DO - 10.1007/s11033-009-9855-1 ID - Xian2010 ER - TY - JOUR AU - Ling, M. T. AU - Chiu, Y. T. AU - Lee, T. K. AU - Leung, S. C. AU - Fung, M. K. AU - Wang, X. AU - Wong, K. F. AU - Wong, Y. C. PY - 2008 DA - 2008// TI - Id-1 induces proteasome-dependent degradation of the HBX protein JO - J Mol Biol VL - 382 UR - https://doi.org/10.1016/j.jmb.2007.06.020 DO - 10.1016/j.jmb.2007.06.020 ID - Ling2008 ER - TY - JOUR AU - Kido, T. AU - Ou, J. H. AU - Lau, Y. F. PY - 2011 DA - 2011// TI - The X-linked tumor suppressor TSPX interacts and promotes degradation of the hepatitis B viral protein HBx via the proteasome pathway JO - PLoS One VL - 6 UR - https://doi.org/10.1371/journal.pone.0022979 DO - 10.1371/journal.pone.0022979 ID - Kido2011 ER - TY - JOUR AU - Sohn, S. Y. AU - Kim, J. H. AU - Baek, K. W. AU - Ryu, W. S. AU - Ahn, B. Y. PY - 2006 DA - 2006// TI - Turnover of hepatitis B virus X protein is facilitated by Hdj1, a human Hsp40/DnaJ protein JO - Biochem Biophys Res Commun VL - 347 UR - https://doi.org/10.1016/j.bbrc.2006.06.158 DO - 10.1016/j.bbrc.2006.06.158 ID - Sohn2006 ER - TY - JOUR AU - Yuan, Y. AU - Tian, C. AU - Gong, Q. AU - Shang, L. AU - Zhang, Y. AU - Jin, C. AU - He, F. AU - Wang, J. PY - 2015 DA - 2015// TI - Interactome map reveals phospholipid scramblase 1 as a novel regulator of hepatitis B virus x protein JO - J Proteome Res VL - 14 UR - https://doi.org/10.1021/pr500943x DO - 10.1021/pr500943x ID - Yuan2015 ER - TY - JOUR AU - Hodgson, A. m. a. n. d. a. J. AU - Hyser, J. o. s. e. p. h. M. AU - Keasler, V. i. c. t. o. r. V. AU - Cang, Y. o. n. g. AU - Slagle, B. e. t. t. y. L. PY - 2012 DA - 2012// TI - Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication JO - Virology VL - 426 UR - https://doi.org/10.1016/j.virol.2012.01.021 DO - 10.1016/j.virol.2012.01.021 ID - Hodgson2012 ER - TY - JOUR AU - Minor, M. M. AU - Slagle, B. L. PY - 2014 DA - 2014// TI - Hepatitis B virus HBx protein interactions with the ubiquitin proteasome system JO - Viruses. VL - 6 UR - https://doi.org/10.3390/v6114683 DO - 10.3390/v6114683 ID - Minor2014 ER - TY - JOUR AU - Bergametti, F. AU - Sitterlin, D. AU - Transy, C. PY - 2002 DA - 2002// TI - Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex JO - J Virol VL - 76 UR - https://doi.org/10.1128/JVI.76.13.6495-6501.2002 DO - 10.1128/JVI.76.13.6495-6501.2002 ID - Bergametti2002 ER - TY - STD TI - Liu N, Zhang J, Yang X, Jiao T, Zhao X, Li W, Zhu J, Yang P, Jin J, Peng J, et al. HDM2 promotes NEDDylation of hepatitis B virus HBx to enhance its stability and function. J Virol. 2017;91. ID - ref39 ER - TY - JOUR AU - Yeom, S. AU - Jeong, H. AU - Kim, S. S. AU - Jang, K. L. PY - 2018 DA - 2018// TI - Hepatitis B virus X protein activates proteasomal activator 28 gamma expression via upregulation of p53 levels to stimulate virus replication JO - J Gen Virol VL - 99 UR - https://doi.org/10.1099/jgv.0.001054 DO - 10.1099/jgv.0.001054 ID - Yeom2018 ER - TY - STD TI - Lee AR, Lim KH, Park ES, Kim DH, Park YK, Park S, Kim DS, Shin GC, Kang HS, Won J, et al. Multiple functions of cellular FLIP are essential for replication of hepatitis B virus. J Virol. 2018;92(16):e00339-18. ID - ref41 ER - TY - STD TI - Saeed U, Kim J, Piracha ZZ, Kwon H, Jung J, Chwae YJ, Park S, Shin HJ, Kim K. Parvulin 14 and parvulin 17 bind to HBx and cccDNA and upregulate HBV replication from cccDNA to virion in a HBx-dependent manner. J Virol. 2018;93(6) pii: e01840-18. ID - ref42 ER - TY - JOUR AU - Cho, H. K. AU - Kim, S. Y. AU - Yoo, S. K. AU - Choi, Y. H. AU - Cheong, J. PY - 2014 DA - 2014// TI - Fatty acids increase hepatitis B virus X protein stabilization and HBx-induced inflammatory gene expression JO - FEBS J VL - 281 UR - https://doi.org/10.1111/febs.12776 DO - 10.1111/febs.12776 ID - Cho2014 ER - TY - JOUR AU - Su, Z. J. AU - Cao, J. S. AU - Wu, Y. F. AU - Chen, W. N. AU - Lin, X. AU - Wu, Y. L. PY - 2017 DA - 2017// TI - Deubiquitylation of hepatitis B virus X protein (HBx) by ubiquitin-specific peptidase 15 (USP15) increases HBx stability and its transactivation activity JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/srep40246 DO - 10.1038/srep40246 ID - Su2017 ER - TY - STD TI - Xu W, Ma C, Zhang Q, Zhao R, Hu D, Zhang X, Chen J, Liu F, Wu K, Liu Y, Wu J. PJA1 coordinates with the SMC5/6 complex to restrict DNA viruses and Episomal genes through interferon-independent manner. J Virol. 2018;92(22) pii: e00825-18. ID - ref45 ER - TY - JOUR AU - Decorsiere, A. AU - Mueller, H. AU - Breugel, P. C. AU - Abdul, F. AU - Gerossier, L. AU - Beran, R. K. AU - Livingston, C. M. AU - Niu, C. AU - Fletcher, S. P. AU - Hantz, O. AU - Strubin, M. PY - 2016 DA - 2016// TI - Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor JO - Nature. VL - 531 UR - https://doi.org/10.1038/nature17170 DO - 10.1038/nature17170 ID - Decorsiere2016 ER - TY - JOUR AU - Slagle, B. L. AU - Andrisani, O. M. AU - Bouchard, M. J. AU - Lee, C. G. AU - Ou, J. H. AU - Siddiqui, A. PY - 2015 DA - 2015// TI - Technical standards for hepatitis B virus X protein (HBx) research JO - Hepatology. VL - 61 UR - https://doi.org/10.1002/hep.27360 DO - 10.1002/hep.27360 ID - Slagle2015 ER - TY - JOUR AU - Zhang, Z. AU - Sun, E. AU - Ou, J. H. AU - Liang, T. J. PY - 2010 DA - 2010// TI - Inhibition of cellular proteasome activities mediates HBX-independent hepatitis B virus replication in vivo JO - J Virol VL - 84 UR - https://doi.org/10.1128/JVI.00579-10 DO - 10.1128/JVI.00579-10 ID - Zhang2010 ER - TY - JOUR AU - Gao, Y. AU - Feng, J. AU - Yang, G. AU - Zhang, S. AU - Liu, Y. AU - Bu, Y. AU - Sun, M. AU - Zhao, M. AU - Chen, F. AU - Zhang, W. PY - 2017 DA - 2017// TI - Hepatitis B virus X protein-elevated MSL2 modulates hepatitis B virus covalently closed circular DNA by inducing degradation of APOBEC3B to enhance hepatocarcinogenesis JO - Hepatology. VL - 66 UR - https://doi.org/10.1002/hep.29316 DO - 10.1002/hep.29316 ID - Gao2017 ER - TY - STD TI - van de Klundert MA, van den Biggelaar M, Kootstra NA, Zaaijer HL. Hepatitis B virus protein X induces degradation of Talin-1. Viruses. 2016;8. ID - ref50 ER - TY - JOUR AU - Zhang, S. AU - Guo, J. T. AU - Wu, J. Z. AU - Yang, G. PY - 2013 DA - 2013// TI - Identification and characterization of multiple TRIM proteins that inhibit hepatitis B virus transcription JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0070001 DO - 10.1371/journal.pone.0070001 ID - Zhang2013 ER - TY - JOUR AU - Gao, B. AU - Duan, Z. AU - Xu, W. AU - Xiong, S. PY - 2009 DA - 2009// TI - Tripartite motif-containing 22 inhibits the activity of hepatitis B virus core promoter, which is dependent on nuclear-located RING domain JO - Hepatology. VL - 50 UR - https://doi.org/10.1002/hep.23011 DO - 10.1002/hep.23011 ID - Gao2009 ER - TY - JOUR AU - Lim, K. H. AU - Park, E. S. AU - Kim, D. H. AU - Cho, K. C. AU - Kim, K. P. AU - Park, Y. K. AU - Ahn, S. H. AU - Park, S. H. AU - Kim, K. H. PY - 2018 DA - 2018// TI - Suppression of interferon-mediated anti-HBV response by single CpG methylation in the 5′-UTR of TRIM22 JO - Gut. VL - 67 UR - https://doi.org/10.1136/gutjnl-2016-312742 DO - 10.1136/gutjnl-2016-312742 ID - Lim2018 ER - TY - JOUR AU - Diab, A. AU - Foca, A. AU - Zoulim, F. AU - Durantel, D. AU - Andrisani, O. PY - 2018 DA - 2018// TI - The diverse functions of the hepatitis B core/capsid protein (HBc) in the viral life cycle: implications for the development of HBc-targeting antivirals JO - Antivir Res VL - 149 UR - https://doi.org/10.1016/j.antiviral.2017.11.015 DO - 10.1016/j.antiviral.2017.11.015 ID - Diab2018 ER - TY - JOUR AU - Rost, M. AU - Mann, S. AU - Lambert, C. AU - Doring, T. AU - Thome, N. AU - Prange, R. PY - 2006 DA - 2006// TI - Gamma-adaptin, a novel ubiquitin-interacting adaptor, and Nedd4 ubiquitin ligase control hepatitis B virus maturation JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M603517200 DO - 10.1074/jbc.M603517200 ID - Rost2006 ER - TY - JOUR AU - Busca, A. AU - Kumar, A. PY - 2014 DA - 2014// TI - Innate immune responses in hepatitis B virus (HBV) infection JO - Virol J VL - 11 UR - https://doi.org/10.1186/1743-422X-11-22 DO - 10.1186/1743-422X-11-22 ID - Busca2014 ER - TY - JOUR AU - Pei, R. J. AU - Chen, X. W. AU - Lu, M. J. PY - 2014 DA - 2014// TI - Control of hepatitis B virus replication by interferons and toll-like receptor signaling pathways JO - World J Gastroenterol VL - 20 UR - https://doi.org/10.3748/wjg.v20.i33.11618 DO - 10.3748/wjg.v20.i33.11618 ID - Pei2014 ER - TY - JOUR AU - Khan, M. AU - Syed, G. H. AU - Kim, S. J. AU - Siddiqui, A. PY - 2016 DA - 2016// TI - Hepatitis B virus-induced Parkin-dependent recruitment of linear ubiquitin assembly complex (LUBAC) to mitochondria and attenuation of innate immunity JO - PLoS Pathog VL - 12 UR - https://doi.org/10.1371/journal.ppat.1005693 DO - 10.1371/journal.ppat.1005693 ID - Khan2016 ER - TY - JOUR AU - Jiang, J. AU - Tang, H. PY - 2010 DA - 2010// TI - Mechanism of inhibiting type I interferon induction by hepatitis B virus X protein JO - Protein Cell VL - 1 UR - https://doi.org/10.1007/s13238-010-0141-8 DO - 10.1007/s13238-010-0141-8 ID - Jiang2010 ER - TY - JOUR AU - Wei, C. AU - Ni, C. AU - Song, T. AU - Liu, Y. AU - Yang, X. AU - Zheng, Z. AU - Jia, Y. AU - Yuan, Y. AU - Guan, K. AU - Xu, Y. PY - 2010 DA - 2010// TI - The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein JO - J Immunol VL - 185 UR - https://doi.org/10.4049/jimmunol.0903874 DO - 10.4049/jimmunol.0903874 ID - Wei2010 ER - TY - JOUR AU - Hong, Y. AU - Zhou, L. AU - Xie, H. AU - Zheng, S. PY - 2015 DA - 2015// TI - Innate immune evasion by hepatitis B virus-mediated downregulation of TRIF JO - Biochem Biophys Res Commun VL - 463 UR - https://doi.org/10.1016/j.bbrc.2015.05.130 DO - 10.1016/j.bbrc.2015.05.130 ID - Hong2015 ER - TY - JOUR AU - Liu, Y. AU - Li, J. AU - Chen, J. AU - Li, Y. AU - Wang, W. AU - Du, X. AU - Song, W. AU - Zhang, W. AU - Lin, L. AU - Yuan, Z. PY - 2015 DA - 2015// TI - Hepatitis B virus polymerase disrupts K63-linked ubiquitination of STING to block innate cytosolic DNA-sensing pathways JO - J Virol VL - 89 UR - https://doi.org/10.1128/JVI.02760-14 DO - 10.1128/JVI.02760-14 ID - Liu2015 ER - TY - JOUR AU - Robek, M. D. AU - Wieland, S. F. AU - Chisari, F. V. PY - 2002 DA - 2002// TI - Inhibition of hepatitis B virus replication by interferon requires proteasome activity JO - J Virol VL - 76 UR - https://doi.org/10.1128/JVI.76.7.3570-3574.2002 DO - 10.1128/JVI.76.7.3570-3574.2002 ID - Robek2002 ER - TY - JOUR AU - Tan, G. AU - Xu, F. AU - Song, H. AU - Yuan, Y. AU - Xiao, Q. AU - Ma, F. AU - Qin, F. X. AU - Cheng, G. PY - 2018 DA - 2018// TI - Identification of TRIM14 as a type I IFN-stimulated gene controlling hepatitis B virus replication by targeting HBx JO - Front Immunol VL - 9 UR - https://doi.org/10.3389/fimmu.2018.01872 DO - 10.3389/fimmu.2018.01872 ID - Tan2018 ER - TY - JOUR AU - Carthagena, L. AU - Bergamaschi, A. AU - Luna, J. M. AU - David, A. AU - Uchil, P. D. AU - Margottin-Goguet, F. AU - Mothes, W. AU - Hazan, U. AU - Transy, C. AU - Pancino, G. AU - Nisole, S. PY - 2009 DA - 2009// TI - Human TRIM gene expression in response to interferons JO - PLoS One VL - 4 UR - https://doi.org/10.1371/journal.pone.0004894 DO - 10.1371/journal.pone.0004894 ID - Carthagena2009 ER - TY - JOUR AU - Tan, G. AU - Xiao, Q. AU - Song, H. AU - Ma, F. AU - Xu, F. AU - Peng, D. AU - Li, N. AU - Wang, X. AU - Niu, J. AU - Gao, P. PY - 2018 DA - 2018// TI - Type I IFN augments IL-27-dependent TRIM25 expression to inhibit HBV replication JO - Cell Mol Immunol VL - 15 UR - https://doi.org/10.1038/cmi.2016.67 DO - 10.1038/cmi.2016.67 ID - Tan2018 ER - TY - JOUR AU - Fan, J. B. AU - Arimoto, K. AU - Motamedchaboki, K. AU - Yan, M. AU - Wolf, D. A. AU - Zhang, D. E. PY - 2015 DA - 2015// TI - Identification and characterization of a novel ISG15-ubiquitin mixed chain and its role in regulating protein homeostasis JO - Sci Rep VL - 5 UR - https://doi.org/10.1038/srep12704 DO - 10.1038/srep12704 ID - Fan2015 ER - TY - JOUR AU - Li, L. AU - Lei, Q. S. AU - Zhang, S. J. AU - Kong, L. N. AU - Qin, B. PY - 2016 DA - 2016// TI - Suppression of USP18 potentiates the anti-HBV activity of interferon alpha in HepG2.2.15 cells via JAK/STAT signaling JO - PLoS One VL - 11 UR - https://doi.org/10.1371/journal.pone.0156496 DO - 10.1371/journal.pone.0156496 ID - Li2016 ER - TY - JOUR AU - Kim, J. H. AU - Luo, J. K. AU - Zhang, D. E. PY - 2008 DA - 2008// TI - The level of hepatitis B virus replication is not affected by protein ISG15 modification but is reduced by inhibition of UBP43 (USP18) expression JO - J Immunol VL - 181 UR - https://doi.org/10.4049/jimmunol.181.9.6467 DO - 10.4049/jimmunol.181.9.6467 ID - Kim2008 ER - TY - JOUR AU - Li, Y. AU - Li, S. AU - Duan, X. AU - Chen, Y. AU - Jiao, B. AU - Ye, H. AU - Yao, M. AU - Chen, L. PY - 2016 DA - 2016// TI - Interferon-stimulated gene 15 conjugation stimulates hepatitis B virus production independent of type I interferon signaling pathway in vitro JO - Mediat Inflamm VL - 2016 ID - Li2016 ER - TY - JOUR AU - Ding, F. AU - Xiao, H. AU - Wang, M. AU - Xie, X. AU - Hu, F. PY - 2014 DA - 2014// TI - The role of the ubiquitin-proteasome pathway in cancer development and treatment JO - Front Biosci (Landmark Ed) VL - 19 UR - https://doi.org/10.2741/4254 DO - 10.2741/4254 ID - Ding2014 ER - TY - JOUR AU - Cai, J. AU - Liu, T. AU - Jiang, X. AU - Guo, C. AU - Liu, A. AU - Xiao, X. PY - 2017 DA - 2017// TI - Downregulation of USP18 inhibits growth and induces apoptosis in hepatitis B virus-related hepatocellular carcinoma cells by suppressing BCL2L1 JO - Exp Cell Res VL - 358 UR - https://doi.org/10.1016/j.yexcr.2017.07.006 DO - 10.1016/j.yexcr.2017.07.006 ID - Cai2017 ER - TY - JOUR AU - Kim, S. J. AU - Khan, M. AU - Quan, J. AU - Till, A. AU - Subramani, S. AU - Siddiqui, A. PY - 2013 DA - 2013// TI - Hepatitis B virus disrupts mitochondrial dynamics: induces fission and mitophagy to attenuate apoptosis JO - PLoS Pathog VL - 9 UR - https://doi.org/10.1371/journal.ppat.1003722 DO - 10.1371/journal.ppat.1003722 ID - Kim2013 ER - TY - JOUR AU - Liu, D. AU - Cui, L. AU - Wang, Y. AU - Yang, G. AU - He, J. AU - Hao, R. AU - Fan, C. AU - Qu, M. AU - Liu, Z. AU - Wang, M. PY - 2016 DA - 2016// TI - Hepatitis B e antigen and its precursors promote the progress of hepatocellular carcinoma by interacting with NUMB and decreasing p53 activity JO - Hepatology. VL - 64 UR - https://doi.org/10.1002/hep.28594 DO - 10.1002/hep.28594 ID - Liu2016 ER - TY - JOUR AU - Hsieh, Y. H. AU - Su, I. J. AU - Wang, H. C. AU - Tsai, J. H. AU - Huang, Y. J. AU - Chang, W. W. AU - Lai, M. D. AU - Lei, H. Y. AU - Huang, W. PY - 2007 DA - 2007// TI - Hepatitis B virus pre-S2 mutant surface antigen induces degradation of cyclin-dependent kinase inhibitor p27Kip1 through c-Jun activation domain-binding protein 1 JO - Mol Cancer Res VL - 5 UR - https://doi.org/10.1158/1541-7786.MCR-07-0098 DO - 10.1158/1541-7786.MCR-07-0098 ID - Hsieh2007 ER - TY - JOUR AU - Neuveut, C. AU - Wei, Y. AU - Buendia, M. A. PY - 2010 DA - 2010// TI - Mechanisms of HBV-related hepatocarcinogenesis JO - J Hepatol VL - 52 UR - https://doi.org/10.1016/j.jhep.2009.10.033 DO - 10.1016/j.jhep.2009.10.033 ID - Neuveut2010 ER - TY - JOUR AU - Benhenda, S. AU - Cougot, D. AU - Buendia, M. A. AU - Neuveut, C. PY - 2009 DA - 2009// TI - Hepatitis B virus X protein molecular functions and its role in virus life cycle and pathogenesis JO - Adv Cancer Res VL - 103 UR - https://doi.org/10.1016/S0065-230X(09)03004-8 DO - 10.1016/S0065-230X(09)03004-8 ID - Benhenda2009 ER - TY - JOUR AU - Zhang, Y. AU - Wu, S. S. AU - Chen, X. H. AU - Tang, Z. H. AU - Yu, Y. S. AU - Zang, G. Q. PY - 2017 DA - 2017// TI - Tripartite motif containing 52 (TRIM52) promotes cell proliferation in hepatitis B virus-associated hepatocellular carcinoma JO - Med Sci Monit VL - 23 UR - https://doi.org/10.12659/MSM.907242 DO - 10.12659/MSM.907242 ID - Zhang2017 ER - TY - JOUR AU - Martin-Lluesma, S. AU - Schaeffer, C. AU - Robert, E. I. AU - Breugel, P. C. AU - Leupin, O. AU - Hantz, O. AU - Strubin, M. PY - 2008 DA - 2008// TI - Hepatitis B virus X protein affects S phase progression leading to chromosome segregation defects by binding to damaged DNA binding protein 1 JO - Hepatology. VL - 48 UR - https://doi.org/10.1002/hep.22542 DO - 10.1002/hep.22542 ID - Martin-Lluesma2008 ER - TY - JOUR AU - Pan, Y. AU - Wang, B. AU - Yang, X. AU - Bai, F. AU - Xu, Q. AU - Li, X. AU - Gao, L. AU - Ma, C. AU - Liang, X. PY - 2015 DA - 2015// TI - CUL4A facilitates hepatocarcinogenesis by promoting cell cycle progression and epithelial-mesenchymal transition JO - Sci Rep VL - 5 UR - https://doi.org/10.1038/srep17006 DO - 10.1038/srep17006 ID - Pan2015 ER - TY - JOUR AU - Zhang, H. AU - Diab, A. AU - Fan, H. AU - Mani, S. K. AU - Hullinger, R. AU - Merle, P. AU - Andrisani, O. PY - 2015 DA - 2015// TI - PLK1 and HOTAIR accelerate proteasomal degradation of SUZ12 and ZNF198 during hepatitis B virus-induced liver carcinogenesis JO - Cancer Res VL - 75 UR - https://doi.org/10.1158/0008-5472.CAN-14-2928 DO - 10.1158/0008-5472.CAN-14-2928 ID - Zhang2015 ER - TY - JOUR AU - Gabay, M. AU - Li, Y. AU - Felsher, D. W. PY - 2014 DA - 2014// TI - MYC Activation Is a Hallmark of Cancer Initiation and Maintenance JO - Cold Spring Harbor Perspectives in Medicine VL - 4 UR - https://doi.org/10.1101/cshperspect.a014241 DO - 10.1101/cshperspect.a014241 ID - Gabay2014 ER - TY - JOUR AU - Lee, S. AU - Kim, W. AU - Ko, C. AU - Ryu, W. S. PY - 2016 DA - 2016// TI - Hepatitis B virus X protein enhances Myc stability by inhibiting SCF (Skp2) ubiquitin E3 ligase-mediated Myc ubiquitination and contributes to oncogenesis JO - Oncogene. VL - 35 UR - https://doi.org/10.1038/onc.2015.251 DO - 10.1038/onc.2015.251 ID - Lee2016 ER - TY - JOUR AU - Kalra, N. AU - Kumar, V. PY - 2006 DA - 2006// TI - The X protein of hepatitis B virus binds to the F box protein Skp2 and inhibits the ubiquitination and proteasomal degradation of c-Myc JO - FEBS Lett VL - 580 UR - https://doi.org/10.1016/j.febslet.2005.12.034 DO - 10.1016/j.febslet.2005.12.034 ID - Kalra2006 ER - TY - JOUR AU - Cao, K. AU - Gong, H. AU - Qiu, Z. AU - Wen, Q. AU - Zhang, B. AU - Tang, T. AU - Zhou, X. AU - Cao, T. AU - Wang, B. AU - Shi, H. AU - Wang, R. PY - 2016 DA - 2016// TI - Hepatitis B virus X protein reduces the stability of Nrdp1 to up-regulate ErbB3 in hepatocellular carcinoma cells JO - Tumour Biol VL - 37 UR - https://doi.org/10.1007/s13277-016-4936-y DO - 10.1007/s13277-016-4936-y ID - Cao2016 ER - TY - JOUR AU - Ali, A. AU - Abdel-Hafiz, H. AU - Suhail, M. AU - Al-Mars, A. AU - Zakaria, M. K. AU - Fatima, K. AU - Ahmad, S. AU - Azhar, E. AU - Chaudhary, A. AU - Qadri, I. PY - 2014 DA - 2014// TI - Hepatitis B virus, HBx mutants and their role in hepatocellular carcinoma JO - World J Gastroenterol VL - 20 UR - https://doi.org/10.3748/wjg.v20.i30.10238 DO - 10.3748/wjg.v20.i30.10238 ID - Ali2014 ER - TY - JOUR AU - Huang, Y. AU - Tong, S. AU - Tai, A. W. AU - Hussain, M. AU - Lok, A. S. PY - 2011 DA - 2011// TI - Hepatitis B virus core promoter mutations contribute to hepatocarcinogenesis by deregulating SKP2 and its target, p21 JO - Gastroenterology. VL - 141 UR - https://doi.org/10.1053/j.gastro.2011.06.048 DO - 10.1053/j.gastro.2011.06.048 ID - Huang2011 ER - TY - JOUR AU - Qian, Y. AU - Wang, B. AU - Ma, A. AU - Zhang, L. AU - Xu, G. AU - Ding, Q. AU - Jing, T. AU - Wu, L. AU - Liu, Y. AU - Yang, Z. PY - 2016 DA - 2016// TI - USP16 downregulation by carboxyl-terminal truncated HBx promotes the growth of hepatocellular carcinoma cells JO - Sci Rep VL - 6 UR - https://doi.org/10.1038/srep33039 DO - 10.1038/srep33039 ID - Qian2016 ER - TY - JOUR AU - Molina-Jimenez, F. AU - Benedicto, I. AU - Murata, M. AU - Martin-Vilchez, S. AU - Seki, T. AU - Antonio Pintor-Toro, J. AU - Tortolero, M. AU - Moreno-Otero, R. AU - Okazaki, K. AU - Koike, K. PY - 2010 DA - 2010// TI - Expression of pituitary tumor-transforming gene 1 (PTTG1)/securin in hepatitis B virus (HBV)-associated liver diseases: evidence for an HBV X protein-mediated inhibition of PTTG1 ubiquitination and degradation JO - Hepatology. VL - 51 UR - https://doi.org/10.1002/hep.23468 DO - 10.1002/hep.23468 ID - Molina-Jimenez2010 ER - TY - JOUR AU - Liu, Y. AU - Tong, Z. AU - Li, T. AU - Chen, Q. AU - Zhuo, L. AU - Li, W. AU - Wu, R. C. AU - Yu, C. PY - 2012 DA - 2012// TI - Hepatitis B virus X protein stabilizes amplified in breast cancer 1 protein and cooperates with it to promote human hepatocellular carcinoma cell invasiveness JO - Hepatology. VL - 56 UR - https://doi.org/10.1002/hep.25751 DO - 10.1002/hep.25751 ID - Liu2012 ER - TY - JOUR AU - Kong, F. AU - You, H. AU - Tang, R. AU - Zheng, K. PY - 2017 DA - 2017// TI - The regulation of proteins associated with the cytoskeleton by hepatitis B virus X protein during hepatocarcinogenesis JO - Oncol Lett VL - 13 UR - https://doi.org/10.3892/ol.2017.5757 DO - 10.3892/ol.2017.5757 ID - Kong2017 ER - TY - JOUR AU - Jung, J. K. AU - Kwun, H. J. AU - Lee, J. O. AU - Arora, P. AU - Jang, K. L. PY - 2007 DA - 2007// TI - Hepatitis B virus X protein differentially affects the ubiquitin-mediated proteasomal degradation of beta-catenin depending on the status of cellular p53 JO - J Gen Virol. VL - 88 UR - https://doi.org/10.1099/vir.0.82836-0 DO - 10.1099/vir.0.82836-0 ID - Jung2007 ER - TY - JOUR AU - Shin Kim, S. AU - Yeom, S. AU - Kwak, J. AU - Ahn, H. J. AU - Lib Jang, K. PY - 2016 DA - 2016// TI - Hepatitis B virus X protein induces epithelial-mesenchymal transition by repressing E-cadherin expression via upregulation of E12/E47 JO - J Gen Virol. VL - 97 UR - https://doi.org/10.1099/jgv.0.000324 DO - 10.1099/jgv.0.000324 ID - Shin Kim2016 ER - TY - JOUR AU - Zhang, H. AU - Huang, C. AU - Wang, Y. AU - Lu, Z. AU - Zhuang, N. AU - Zhao, D. AU - He, J. AU - Shi, L. PY - 2015 DA - 2015// TI - Hepatitis B virus X protein sensitizes TRAIL-induced hepatocyte apoptosis by inhibiting the E3 ubiquitin ligase A20 JO - PLoS One VL - 10 UR - https://doi.org/10.1371/journal.pone.0127329 DO - 10.1371/journal.pone.0127329 ID - Zhang2015 ER - TY - JOUR AU - Moon, E. J. AU - Jeong, C. H. AU - Jeong, J. W. AU - Kim, K. R. AU - Yu, D. Y. AU - Murakami, S. AU - Kim, C. W. AU - Kim, K. W. PY - 2004 DA - 2004// TI - Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1alpha JO - FASEB J VL - 18 UR - https://doi.org/10.1096/fj.03-0153fje DO - 10.1096/fj.03-0153fje ID - Moon2004 ER - TY - JOUR AU - Wang, C. AU - Wang, M. D. AU - Cheng, P. AU - Huang, H. AU - Dong, W. AU - Zhang, W. W. AU - Li, P. P. AU - Lin, C. AU - Pan, Z. Y. AU - Wu, M. C. AU - Zhou, W. P. PY - 2017 DA - 2017// TI - Hepatitis B virus X protein promotes the stem-like properties of OV6(+) cancer cells in hepatocellular carcinoma JO - Cell Death Dis VL - 8 UR - https://doi.org/10.1038/cddis.2016.493 DO - 10.1038/cddis.2016.493 ID - Wang2017 ER - TY - JOUR AU - Kim, K. AU - Kim, K. H. AU - Cheong, J. PY - 2010 DA - 2010// TI - Hepatitis B virus X protein impairs hepatic insulin signaling through degradation of IRS1 and induction of SOCS3 JO - PLoS One VL - 5 UR - https://doi.org/10.1371/journal.pone.0008649 DO - 10.1371/journal.pone.0008649 ID - Kim2010 ER - TY - JOUR AU - Motavaf, M. AU - Safari, S. AU - Saffari Jourshari, M. AU - Alavian, S. M. PY - 2013 DA - 2013// TI - Hepatitis B virus-induced hepatocellular carcinoma: the role of the virus x protein JO - Acta Virol VL - 57 UR - https://doi.org/10.4149/av_2013_04_389 DO - 10.4149/av_2013_04_389 ID - Motavaf2013 ER - TY - JOUR AU - Pereira, P. H. S. AU - Curra, C. AU - Garcia, C. R. S. PY - 2018 DA - 2018// TI - Ubiquitin proteasome system as a potential drug target for malaria JO - Curr Top Med Chem VL - 18 UR - https://doi.org/10.2174/1568026618666180427145308 DO - 10.2174/1568026618666180427145308 ID - Pereira2018 ER - TY - JOUR AU - Goru, S. K. AU - Kadakol, A. AU - Gaikwad, A. B. PY - 2017 DA - 2017// TI - Hidden targets of ubiquitin proteasome system: to prevent diabetic nephropathy JO - Pharmacol Res VL - 120 UR - https://doi.org/10.1016/j.phrs.2017.03.024 DO - 10.1016/j.phrs.2017.03.024 ID - Goru2017 ER - TY - JOUR AU - Chen, Y. J. AU - Wu, H. AU - Shen, X. Z. PY - 2016 DA - 2016// TI - The ubiquitin-proteasome system and its potential application in hepatocellular carcinoma therapy JO - Cancer Lett VL - 379 UR - https://doi.org/10.1016/j.canlet.2015.06.023 DO - 10.1016/j.canlet.2015.06.023 ID - Chen2016 ER -