Table 5 Characteristics of patients in the low HBV viral load group according to Sp1 and the G2765A substitution
Sp1 | G2765A | ||||
|---|---|---|---|---|---|
Wild type (n = 12) | Substitution (n = 12) | p | Substitution (n = 8) | p | |
Male (n (%)) | 4 (33.3%) | 9 (75.0%) | 0.1 | 6 (75.0%) | 0.170 |
Age (years) | 53.9 (35–81) | 58.2 (32–74) | 0.522 | 63.4 (46–74) | 0.150 |
HBV DNA (log IU/ml) | 3.9 (1.3–4.4) | 3.2 (1.3–3.5) | 0.061 | 2.2 (1.3–3.0) | 0.040 |
HBsAg (IU/ml) | 4129 (8.61–18,268) | 4483 (37.7–19,986) | 0.525 | 2007 (37.7–6670) | 0.340 |
HBeAg positive (n (%)) | 0 (0%) | 0 (0%) | > 0.999 | 0 (0%) | > 0.999 |
HBeAb positive (n (%)) | 12 (100%) | 12 (100%) | > 0.999 | 8 (100%) | > 0.999 |
AST (U/L) | 26.8 (19–50) | 22.0 (11–40) | 0.074 | 19.0 (11–24) | 0.011 |
ALT (U/L) | 31.9 (14–90) | 20.2 (11–40) | 0.235 | 18.8 (10–27) | 0.162 |
Platelet count (104/μl) | 17.7 (13.9–22.5) | 17.4 (10.9–22.6) | 0.921 | 17.5 (10.9–22.6) | 0.955 |