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Table 3 G2765A substitution ratios determined by TA cloning or next-generation sequencing

From: A substitution in the pre-S1 promoter region is associated with the viral regulation of hepatitis B virus

TA cloninga

Substitution percentage

NGSa

Substitution percentage

1/15

6.67%

44/6155

0.71%

0/15

0.00%

1/3955

0.03%

0/15

0.00%

10/5327

0.19%

9/15

60.00%

4866/8081

60.22%

0/16

0.00%

7/10409

0.07%

0/15

0.00%

2/7304

0.03%

0/15

0.00%

9/6662

0.14%

1/25

4.00%

22/6258

0.35%

1/16

6.25%

49/1643

2.98%

0/15

0.00%

1/2740

0.04%

  1. These samples were selected from high HBV viral load (8.2–7.2 log IU/ml) patients
  2. a Number of samples with the G2765A substitution/total number of samples
  3. Abbreviation: NGS next-generation sequencing
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Virology Journal

ISSN: 1743-422X