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Table 2 Characteristics of patients with pre-S1 promoter mutant or wild-type HBV

From: A substitution in the pre-S1 promoter region is associated with the viral regulation of hepatitis B virus

 

All (n = 35)

Wild type (n = 22)

Mutation (n = 13)

p

Male (n (%))

20 (57.1%)

10 (45.5%)

10 (76.9%)

0.089

Age (years)

51.7 (15–81)

49.2 (15–81)

55.9 (29–74)

0.432

HBV DNA (log IU/ml)

5.11 (1.3–8.2)

5.22 (1.3–8.2)

2.86 (1.3–8.2)

0.003

HBsAg (IU/ml)

13,499 (8.61–151,233)

17,788 (8.61–151,233)

5634 (37.7–19,986)

0.094

HBeAg positive (n (%))

11 (31.4%)

10 (45.5%)

1 (7.7%)

0.027

HBeAb positive (n (%))

24 (68.6%)

12 (54.5%)

12 (92.3%)

0.027

AST (U/L)

34.5 (11–204)

41.4 (16–204)

22.7 (11–40)

0.035

ALT (U/L)

43.8 (10–425)

56.5 (14–425)

22.4 (10–49)

0.127

Platelet count (104/μl)

18.5 (10.9–24.2)

18.8 (13.9–23.9)

18.0 (10.9–24.2)

0.705

  1. Abbreviations: HBV hepatitis B virus, HBsAg hepatitis B surface antigen, HBeAg hepatitis B e antigen, HBeAb hepatitis B e antibody, AST aspartate transaminase, ALT alanine transaminase