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Table 8 Optimal predicted HLA-I-restricted epitopes selected from HPV-58 E6 and E7

From: Identification of variants and therapeutic epitopes in HPV-33/HPV-58 E6 and E7 in Southwest China

Target protein

Start

Length

Peptide

PercentileRank

Binding Core in HLA-II predicted epitopes

HPV-58 E6

40

11

SEVYDFVFADL

0.2

EVYDFVFAD

41

11

EVYDFVFADLR

0.2

EVYDFVFAD

44

12

DFVFADLRIVYR

0.2

DFVFADLRI/FVFADLRIV

45

10

FVFADLRIVY

0.1

FVFADLRIV

47

14

FADLRIVYRDGNPF

0.2

IVYRDGNPF

61

12

AVCKVCLRLLSK

0.1

CKVCLRLLS

71

13

SKISEYRHYNYSL

0.1

 

HPV-58 E7

49

12

ATANYYIVTCCY

0.5

 

78

8

RTLQQLLM

0.2

 

78

14

RTLQQLLMGTCTIV

0.4

 

79

13

TLQQLLMGTCTIV

0.5

 

82

10

QLLMGTCTIV

0.45

 

83

9

LLMGTCTIV

0.4

 
  1. Note: The column of “Binding Core in HLA-II predicted epitopes” refers to the binding core of predicted HLA-II epitopes present in the optimal HLA-I epitopes