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Table 8 Optimal predicted HLA-I-restricted epitopes selected from HPV-58 E6 and E7

From: Identification of variants and therapeutic epitopes in HPV-33/HPV-58 E6 and E7 in Southwest China

Target protein Start Length Peptide PercentileRank Binding Core in HLA-II predicted epitopes
HPV-58 E6 40 11 SEVYDFVFADL 0.2 EVYDFVFAD
41 11 EVYDFVFADLR 0.2 EVYDFVFAD
44 12 DFVFADLRIVYR 0.2 DFVFADLRI/FVFADLRIV
45 10 FVFADLRIVY 0.1 FVFADLRIV
47 14 FADLRIVYRDGNPF 0.2 IVYRDGNPF
61 12 AVCKVCLRLLSK 0.1 CKVCLRLLS
71 13 SKISEYRHYNYSL 0.1  
HPV-58 E7 49 12 ATANYYIVTCCY 0.5  
78 8 RTLQQLLM 0.2  
78 14 RTLQQLLMGTCTIV 0.4  
79 13 TLQQLLMGTCTIV 0.5  
82 10 QLLMGTCTIV 0.45  
83 9 LLMGTCTIV 0.4  
  1. Note: The column of “Binding Core in HLA-II predicted epitopes” refers to the binding core of predicted HLA-II epitopes present in the optimal HLA-I epitopes