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Table 5 Secondary structure prediction of HPV-33/58 E6 and E7

From: Identification of variants and therapeutic epitopes in HPV-33/HPV-58 E6 and E7 in Southwest China

Target protein Sequence type No. helix/Helicesa No. sheet/Sheetsb No. coil/Coilsc Accessibility type
Burred Exposed
HPV-33 E6 Reference 41/27.52% 31/20.80% 77/51.68% 50/33.56% 99/66.44%
  Variant 42/28.19% 24/16.11% 83/55.70% 49/32.89% 100/67.11%
HPV-58 E6 Reference 41/27.52% 25/16.78% 83/55.70% 48/32.22% 101/67.78%
  Variant 42/28.19% 25/16.78% 82/55.03% 48/32.22% 101/67.78%
HPV-33 E7 Reference 12/12.37% 16/16.50% 69/71.13% 27/27.84% 70/72.16%
  Variant-1 11/11.34% 16/16.50% 70/72.16% 30/30.93% 67/69.07%
  Variant-2 11/11.34% 16/16.50% 70/72.16% 28/28.87% 69/71.13%
HPV-58 E7 Reference 12/12.24% 17/17.35% 69/70.41% 28/28.57% 70/71.43%
  Variant-1 12/12.24% 17/17.35% 69/70.41% 26/26.53% 72/73.47%
  Variant-2 12/12.24% 17/17.35% 69/70.41% 26/26.53% 72/73.47%
  1. Note: In the sequence type column, ‘reference’ and ‘variant’ indicate the reference sequence and variant sequence of the corresponding protein, respectively. ‘No. helix/Helicesa’, ‘No. sheet/Sheetsb’ and ‘No. coil/Coilsc’ represent the number/ratio of residues located in helix, sheet and coil, respectively. ‘Burred’ and ‘Exposed’ represent the number/ratio of residues burred in protein and exposed at the surface, respectively