Table 3 Nucleotide variations and amino acid substitutions in HPV-33 E6 and E7
From: Identification of variants and therapeutic epitopes in HPV-33/HPV-58 E6 and E7 in Southwest China
HPV-33 | E6 | E7 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
S. No. | M1 | M2 | M3 | M4 | M5 | M6 | M7 | M8 | M1 | M2 | M3 | M4 |
Position | 213 | 273 | 329 | 364 | 387 | 446 | 542 | 549 | 658 | 706 | 706 | 862 |
Ref | A | A | G | A | A | A | G | T | G | C | C | A |
Normal | – | – | – | – | – | – | – | – | – | – | – | – |
 A | – | – | – | – | – | – | – | – | – | – | A | – |
 T | – | – | – | – | – | – | T | – | – | T | – | T |
 G | – | G | – | – | – | G | – | C | – | – | – | – |
 C | C | – | C | C | C | – | – | – | C | – | – | – |
Frequency | 42 | 17 | 7 | 16 | 42 | 16 | 33 | 25 | 16 | 36 | 27 | 19 |
% of Samples | 19.44 | 7.87 | 3.24 | 7.41 | 19.44 | 7.41 | 15.28 | 11.57 | 7.4 | 16.67 | 12.5 | 8.8 |
Amino acid Mutation | K35N | – | S74T | N86H | K93N | Q113R | R145I | – | S29T | A45V | A45E | Q97L |
Secondary structure | C | S | H | C | C | H | C | C | C | C | C | C |