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Table 1 Predicted protease cleavage sites of the DHAV polyprotein

From: Biochemical characterization of recombinant Avihepatovirus 3C protease and its localization

Protein aa position Length Cleavage site GC content Cleavage type
1AB/VP0 1–256 256 aa PFDNQ/GKRKP 40% 3Cpro
1C/VP3 257–493 237 aa ATNNQ/GDTNQ 43.33% 3Cpro
1D/VP1 494–731 238 aa DLEIE/SDQIR 33.33% 3Cpro
2A1 732–751 20 aa EPNPG/PILVV 46.47% ribosome skipping site
2A2 752–912 161 aa PEFVS/HLPRL 43.33% 3Cpro
2A3 913–1036 124 aa ITTDQ/SFPGK 36.67% 3Cpro
2B 1037–1155 119 aa MLEDQ/SGKTT 43.33% 3Cpro
2C 1156–1488 333 aa SFMNQ/SKVRR 46.67% 3Cpro
3A 1489–1581 93 aa RRFAQ/SIYSQ 40% 3Cpro
3B 1582–1613 32 aa TGLDQ/SGRVN 53.33% 3Cpro
3C 1614–1794 181 aa PVFNQ/GKVVS 40% 3Cpro
3D 1795–2247 453 aa