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Table 1 Baseline characteristics of responders and non-responders

From: Serum hepatitis B virus RNA levels as a predictor of HBeAg seroconversion during treatment with peginterferon alfa-2a

Variables Overall populations Responders Non-responders P value
Number 61 22 39
Age (year) 33.0 (23–57) 31.0 (23–57) 36.5 (23–57) 0.043
Male(%) 46 (75) 16 (73) 30 (77) 0.493
ALT (IU/L) 120.0 (13–603) 175.0 (43–575) 88.0 (13–603) 0.025
AST (IU/L) 89.0 (21–435) 140.0 (36–435) 68.0 (21–399) 0.031
HBV RNA (log10 copies/mL) 5.37 ± 1.32 4.55 ± 1.19 5.90 ± 1.13 0.001
HBV DNA (log10 copies/mL) 6.72 ± 1.91 5.76 ± 2.24 7.15 ± 1.59 0.036
HBsAg (log10 IU/mL) 3.89 ± 0.71 3.25 ± 0.63 4.24 ± 0.53 < 0.001
  1. ALT alanine aminotransferase, AST aspartate aminotransferase, HBsAg hepatitis B surface antigen, HBV DNA hepatitis B deoxyribonucleic acid, HBV RNA hepatitis B ribonucleic acid
  2. Data were expressed as mean values± standard deviation or median (range)