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Table 1 Baseline characteristics of responders and non-responders

From: Serum hepatitis B virus RNA levels as a predictor of HBeAg seroconversion during treatment with peginterferon alfa-2a

Variables

Overall populations

Responders

Non-responders

P value

Number

61

22

39

–

Age (year)

33.0 (23–57)

31.0 (23–57)

36.5 (23–57)

0.043

Male(%)

46 (75)

16 (73)

30 (77)

0.493

ALT (IU/L)

120.0 (13–603)

175.0 (43–575)

88.0 (13–603)

0.025

AST (IU/L)

89.0 (21–435)

140.0 (36–435)

68.0 (21–399)

0.031

HBV RNA (log10 copies/mL)

5.37 ± 1.32

4.55 ± 1.19

5.90 ± 1.13

0.001

HBV DNA (log10 copies/mL)

6.72 ± 1.91

5.76 ± 2.24

7.15 ± 1.59

0.036

HBsAg (log10 IU/mL)

3.89 ± 0.71

3.25 ± 0.63

4.24 ± 0.53

< 0.001

  1. ALT alanine aminotransferase, AST aspartate aminotransferase, HBsAg hepatitis B surface antigen, HBV DNA hepatitis B deoxyribonucleic acid, HBV RNA hepatitis B ribonucleic acid
  2. Data were expressed as mean values± standard deviation or median (range)