|
Beinhardt (2016) [27]
|
10
|
5 (5/5 on dialysis)
|
1 pt.: recurring peritonitis
|
|
1 pt.: renal anemia
|
|
1 pt.: graft failure after orthotopic liver transplantation (LOT)
|
|
1 pt.: cirrhosis due to HCV recurrence after OLT
|
|
1 PT: pneumonia
|
|
Goel (2018) [23]
|
41
|
2 (0/2 on dialysis)
|
1 pt.: acute mild pancreatitis after renal transplantation
|
|
1 pt.: worsening of ascites
|
|
Lawitz (2017) [33]
|
18
|
4 (0/4 on dialysis)
|
1 pt.: acute kidney injury and noncardiac chest pain
|
|
1 pt.: dehydration and hypotension
|
|
1 pt.: acute renal failure
|
|
1 pt.: hypotension and synocope (no SAEs were considered related to study drug)
|
|
Saxena (2015) [47]
|
18
|
3
|
NA
|
|
Cox-North (2017) [35]
|
29
|
1 (1/1 on dialysis)
|
1 pt.: cardiac event (unable to draw any conclusions about the safety of SOF regimens in those with underlying cardiac disease)
|
