From: Efficacy of geraniin on dengue virus type-2 infected BALB/c mice
Histopathological alterations | 0 | 1 | 2 | 3 |
---|---|---|---|---|
Hydropic degeneration (hepatocyte swelling) | None | Mild (small area, ground glass appearance of hepatocytes) | Moderate (larger area, ground glass appearance of hepatocytes) | Diffuse (feathery appearance of hepatocytes) |
Necrosis & haemorrhage | None | Mild (no haemorrhage) | Moderate (small area, focal) | Severe (large area, multifocal) |
Venous outflow congestion (dilatation of sinusoids) | None | Mild (slight) | Moderate (focal) | Severe (diffuse) |
Steatosis | None | Mild (small area, microsteatosis) | Moderate (larger zones, micro- and macrosteatosis) | Severe (diffuse micro- and macrosteatosis) |
Pyknotic nucleus | None | Mild | Moderate | Severe |