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Table 2 Inhibitory activities of compounds against influenza strains

From: DMO-CAP inhibits influenza virus replication by activating heme oxygenase-1-mediated IFN response

 

A/FortMonmouth/1/1947

A/Wuhan/359/1995

 

TC50

(μM)

IC50

(μM)

SI

IC50

(μM)

SI

DMO-CAP

223 ± 0.41

31.78 ± 0.51

7.02

42.91 ± 0.60

5.20

OC

> 487 ± 0.12

0.56 ± 0.09

> 869.64

0.69 ± 0.24

> 705.80

RBV

> 890 ± 0.13

1.02 ± 0.12

> 872.55

1.97 ± 0.22

> 451.78