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Table 3 Characteristics of nine patients with HLA-A*0201

From: Immune reconstitution of HLA-A*0201/BMLF1- and HLA-A*1101/LMP2-specific Epstein Barr virus cytotoxic T lymphocytes within 90 days after haploidentical hematopoietic stem cell transplantation

Patient No

EBV state

Percentages of EBV-CTLs at + 30 days

Percentages of EBV-CTLs at + 60 days

Percentages of EBV-CTLs at + 90 days

Time of CSA withdrawal

aGVHD

Result

Cause of death

1

No

0.1982

2.9100

1.0950

 

no

alive

 

2

EBV-DNAemia

0.8337

1.9200

1.3644

20

Grade I

alive

 

3

No

0.7296

3.0000

1.0119

19

Grade I

alive

 

4

EBV-DNAemia

0.3252

3.1700

1.4483

–

Grade I

alive

 

5

EBV-DNAemia

0.0179

1.9000

1.1990

16

Grade I

alive

 

6

No

1.0790

4.2400

–

11

Grade I

dead

Aspergillus pneumonia

7

EBV-related disease

0.5619

0.6900

–

5

Grade I

dead

EBV encephalitis

8

EBV-related disease

0.2727

0.5300

–

–

no

alive

 

9

EBV-related disease

0.9600

0.5500

–

58

Grade I

dead

EBV enteritis

  1. Note: The patient who died at + 43 days was a 100% donor type by bone puncture and STR examination at + 30 days after transplantation. However, at + 33 days, this patient developed hyperthermia, pulmonary infection, and decreased blood cells and was found to have decreased chimerism to 23% of that of the donor recipient at + 37 days. Secondary graft failure was observed, which was thought to be related to the serious pulmonary fungal infection. We did not include this patient in this Table
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Virology Journal

ISSN: 1743-422X