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Table 3 The dynamic variability of drug susceptibility in 88 HIV/AIDS patients

From: Drug resistance evolution in patients with human immunodeficiency virus-1 under long-term antiretroviral treatment-failure in Yunnan Province, China

Drugs Numbers of drug susceptibility undergo changes Total (N/%)
−4 −3 −2 −1 invariant 1 2 3 4
3TC
 T2 vs T1 4 0 0 0 77 0 0 0 7 11 (12.50)
 T3 vs T2 8 0 0 0 74 1 0 0 5 14 (15.91)
AZT
 T2 vs T1 0 0 1 1 79 1 1 3 2 9 (10.23)
 T3 vs T2 1 1 1 0 81 2 1 0 1 7 (7.95)
D4T
 T2 vs T1 0 0 0 3 75 3 3 2 2 13 (14.77)
 T3 vs T2 2 2 0 0 75 5 2 1 1 13 (14.77)
TDF
 T2 vs T1 0 0 0 2 82 1 1 1 1 6 (6.82)
 T3 vs T2 1 1 1 0 80 1 2 1 1 8 (9.09)
EFV
 T2 vs T1 4 4 1 3 63 4 1 4 4 25 (28.41)
 T3 vs T2 3 4 0 3 68 5 1 0 4 20 (22.73)
ETR
 T2 vs T1 0 2 1 6 60 9 5 5 0 28 (31.82)
 T3 vs T2 0 4 1 3 70 7 1 2 0 18 (20.45)
NVP
 T2 vs T1 6 2 0 3 67 0 3 0 7 21 (23.86)
 T3 vs T2 6 0 0 2 71 3 1 1 4 17 (19.32)
LPV/r
 T2 vs T1 0 0 0 0 86 0 0 1 1 2 (2.27)
 T3 vs T2 1 0 0 0 85 1 0 1 0 3 (3.41)
  1. T2 vs T1: Comparison of second detection and first detection, T3 vs T2: Comparison of third detection and second detection
  2. −4 represent drug resistant degree reduce 4 grades (For example, the first detected result was high level resistance, the second result change to Susceptible), opposite 4 represent drug resistant degree raise 4 grades, the others and the like