Skip to main content

Table 3 The dynamic variability of drug susceptibility in 88 HIV/AIDS patients

From: Drug resistance evolution in patients with human immunodeficiency virus-1 under long-term antiretroviral treatment-failure in Yunnan Province, China

Drugs

Numbers of drug susceptibility undergo changes

Total (N/%)

−4

−3

−2

−1

invariant

1

2

3

4

3TC

 T2 vs T1

4

0

0

0

77

0

0

0

7

11 (12.50)

 T3 vs T2

8

0

0

0

74

1

0

0

5

14 (15.91)

AZT

 T2 vs T1

0

0

1

1

79

1

1

3

2

9 (10.23)

 T3 vs T2

1

1

1

0

81

2

1

0

1

7 (7.95)

D4T

 T2 vs T1

0

0

0

3

75

3

3

2

2

13 (14.77)

 T3 vs T2

2

2

0

0

75

5

2

1

1

13 (14.77)

TDF

 T2 vs T1

0

0

0

2

82

1

1

1

1

6 (6.82)

 T3 vs T2

1

1

1

0

80

1

2

1

1

8 (9.09)

EFV

 T2 vs T1

4

4

1

3

63

4

1

4

4

25 (28.41)

 T3 vs T2

3

4

0

3

68

5

1

0

4

20 (22.73)

ETR

 T2 vs T1

0

2

1

6

60

9

5

5

0

28 (31.82)

 T3 vs T2

0

4

1

3

70

7

1

2

0

18 (20.45)

NVP

 T2 vs T1

6

2

0

3

67

0

3

0

7

21 (23.86)

 T3 vs T2

6

0

0

2

71

3

1

1

4

17 (19.32)

LPV/r

 T2 vs T1

0

0

0

0

86

0

0

1

1

2 (2.27)

 T3 vs T2

1

0

0

0

85

1

0

1

0

3 (3.41)

  1. T2 vs T1: Comparison of second detection and first detection, T3 vs T2: Comparison of third detection and second detection
  2. −4 represent drug resistant degree reduce 4 grades (For example, the first detected result was high level resistance, the second result change to Susceptible), opposite 4 represent drug resistant degree raise 4 grades, the others and the like