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Table 1 The demographic characteristics of 88 HIV/AIDS patients detected genotyping resistance

From: Drug resistance evolution in patients with human immunodeficiency virus-1 under long-term antiretroviral treatment-failure in Yunnan Province, China

Characteristics DR Positive N1 = 54 DR Negative N2 = 34 Total 88 χ2 P
No.(%) No.(%) No.
Gender     0.155 0.812
 Male 33 (61.1) 23 (67.6) 56   
 Female 21 (38.9) 11 (32.4) 32   
Age (years)     5.133a 0.162
 6–20 5 (9.3) 5   
 21–40 36 (66.7) 26 (76.5) 62   
 41–60 13 (24.0) 7 (20.6) 20   
 61–63 1 (2.9) 1   
Marital status     0.329 0.828
 Unmarried 14 (25.9) 7 (20.6) 21   
 Married 25 (46.3) 17 (50.0) 42   
 Divorced or widowed 15 (27.8) 10 (29.4) 25   
Route of transmission     7.550a 0.11
 Blood-born (BB) 2 (3.7) 2   
 Injection Drug user (IDU) 24(44.4) 16 (47.1) 40   
 Heterosexual (HST) 20(37.0) 18 (52.9) 38   
 Mother to Children (MTC) 3(5.6) 3   
 Unknown 5(9.3) 5   
Baseline CD4+ count (cells/μl)     17.682a 0.001
 0–200 27(50.0) 8 (23.5) 35   
 201–350 21(38.9) 21 (61.8) 42   
 351–500 5 (14.7) 5   
 undetected 6(11.1) 6   
Area     9.069a 0.526
 Kunming 13(24.1) 9(26.5) 22   
 Lincang 8(14.8) 6(17.6) 14   
 Honghe 8(14.8) 4(11.8) 12   
 Chuxiong 3(5.6) 6(17.6) 9   
 Nujiang 3(5.6) 3   
 Puer 2(3.7) 2(5.9) 4   
 Zhaotong 6(11.1) 3(8.8) 9   
 Dali 3(5.6) 3(8.8) 6   
 Baoshan 2(3.7) 2   
 Wenshan 4(7.4) 1(2.9) 5   
 Yuxi 2(3.7) 2   
Therapeutic regimen     11.809a 0.107
 3TC + NVP + AZT 19(35.2) 21(61.8) 40   
 3TC + NVP + D4T 16(29.6) 5(14.7) 21   
 EFV + 3TC + AZT 12(22.2) 5(14.7) 17   
 EFV + 3TC + D4T 1(1.9) 3(8.8) 4   
 EFV + 3TC + TDF 3(5.6) 3   
 3TC + AZT + Lpv/r 1(1.9) 1   
 NVP + DDI + D4T 1(1.9) 1   
 Lpv/r + 3TC + ABC 1(1.9) 1   
  1. aFisher’s exact probability Chisquare test. 3TC:Lamivudine, NVP:Nevirapine, D4T:Stavudine, AZT:Zidovudine, EFV:Efavirenz, TDF:Tenofovir disoproxil fumarate Lpv/r:Lopinavir/Ritonavir