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Table 1 The demographic characteristics of 88 HIV/AIDS patients detected genotyping resistance

From: Drug resistance evolution in patients with human immunodeficiency virus-1 under long-term antiretroviral treatment-failure in Yunnan Province, China

Characteristics

DR Positive N1 = 54

DR Negative N2 = 34

Total 88

χ2

P

No.(%)

No.(%)

No.

Gender

   

0.155

0.812

 Male

33 (61.1)

23 (67.6)

56

  

 Female

21 (38.9)

11 (32.4)

32

  

Age (years)

   

5.133a

0.162

 6–20

5 (9.3)

5

  

 21–40

36 (66.7)

26 (76.5)

62

  

 41–60

13 (24.0)

7 (20.6)

20

  

 61–63

1 (2.9)

1

  

Marital status

   

0.329

0.828

 Unmarried

14 (25.9)

7 (20.6)

21

  

 Married

25 (46.3)

17 (50.0)

42

  

 Divorced or widowed

15 (27.8)

10 (29.4)

25

  

Route of transmission

   

7.550a

0.11

 Blood-born (BB)

2 (3.7)

2

  

 Injection Drug user (IDU)

24(44.4)

16 (47.1)

40

  

 Heterosexual (HST)

20(37.0)

18 (52.9)

38

  

 Mother to Children (MTC)

3(5.6)

3

  

 Unknown

5(9.3)

5

  

Baseline CD4+ count (cells/μl)

   

17.682a

0.001

 0–200

27(50.0)

8 (23.5)

35

  

 201–350

21(38.9)

21 (61.8)

42

  

 351–500

5 (14.7)

5

  

 undetected

6(11.1)

6

  

Area

   

9.069a

0.526

 Kunming

13(24.1)

9(26.5)

22

  

 Lincang

8(14.8)

6(17.6)

14

  

 Honghe

8(14.8)

4(11.8)

12

  

 Chuxiong

3(5.6)

6(17.6)

9

  

 Nujiang

3(5.6)

3

  

 Puer

2(3.7)

2(5.9)

4

  

 Zhaotong

6(11.1)

3(8.8)

9

  

 Dali

3(5.6)

3(8.8)

6

  

 Baoshan

2(3.7)

2

  

 Wenshan

4(7.4)

1(2.9)

5

  

 Yuxi

2(3.7)

2

  

Therapeutic regimen

   

11.809a

0.107

 3TC + NVP + AZT

19(35.2)

21(61.8)

40

  

 3TC + NVP + D4T

16(29.6)

5(14.7)

21

  

 EFV + 3TC + AZT

12(22.2)

5(14.7)

17

  

 EFV + 3TC + D4T

1(1.9)

3(8.8)

4

  

 EFV + 3TC + TDF

3(5.6)

3

  

 3TC + AZT + Lpv/r

1(1.9)

1

  

 NVP + DDI + D4T

1(1.9)

1

  

 Lpv/r + 3TC + ABC

1(1.9)

1

  
  1. aFisher’s exact probability Chisquare test. 3TC:Lamivudine, NVP:Nevirapine, D4T:Stavudine, AZT:Zidovudine, EFV:Efavirenz, TDF:Tenofovir disoproxil fumarate Lpv/r:Lopinavir/Ritonavir