Fig. 1.From: Multiple amino acid substitutions involved in the adaption of three avian-origin H7N9 influenza viruses in micePathogenicity of the parental and mouse-adapted H7N9 viruses in mice. Groups of 5 6-week-old female BALB/C mice were inoculated i.n. with 106 EID50 (50 μl) of H7N9-53, H7N9-53 MA, H7N9-MCX, H7N9-MCX MA, H7N9-ZSM, H7N9-ZSM MA and PBS, respectively. Body weight changes and survival rates were monitored daily for 14 days. a Weight changes were recorded daily and represented by means (± standard deviation). b Mortality was determined by percentage of the surviving mice.Back to article page