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Table 1 Comparison of VNT and PRNT assays for a panel of 142 samples

From: Combination of ELISA screening and seroneutralisation tests to expedite Zika virus seroprevalence studies

 

PRNT50

PRNT90

VNT

Positive (titre≥10)

Negative (titre< 10)

Positive (titre≥10)

Negative (titre< 10)

Positive  (titre≥40)

51

1

51

1

Negative (titre<40)

9

81

1

89

Sensitivity of VNT

(95% CI)

85% (51/60)

(72.9–92.4%)

98.1% (51/52)

(88.4–99.9%)

Specificity of VNT

(95% CI)

98.7% (81/82)

(92.4–99.9%)

98.8% (89/90)

(93.1–99.9%)