Fig. 2

Experimental outcomes in Balb/c mice exposed by the aerosol route to a dose range of EEEV Pe-6, or challenge media controls (CM alone). Top left panel; percentage survival post- challenge. Top right panel; percentage change in body weight (from weight taken on day 0 prior to challenge). Bottom left panel; mean clinical scores. Bottom right panel; mean viral titre in tissues of animals that succumbed to disease 3–4 days post-challenge. The legends refer to the titres of input virus (pfu/ml). Data points include mice that were free of clinical signs. Error bars indicate 95% confidence interval. n = 8 except for the bottom right panel, where n = 1–5