Fig. 5
From: A CpG oligodeoxynucleotide enhances the immune response to rabies vaccination in mice
RVNA response induced by reduced doses of HDCV-CpG. Balb/c mice (n = 10) were immunized i.m. with Saline, HDCV, or HDCV (1, 1/2, 1/4 and 1/8 dose) plus CpG for 5 injections. Serum samples were collected on D35. RFFIT was used to detect RVNA in the sera of mice. The antibody titer was expressed in international unit per milliliter (IU/ml) calculated in comparison with the national reference standard serum