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Fig. 2 | Virology Journal

Fig. 2

From: Porcine reproductive and respiratory syndrome virus inhibits MARC-145 proliferation via inducing apoptosis and G2/M arrest by activation of Chk/Cdc25C and p53/p21 pathway

Fig. 2

PRRSV infection induces apoptosis in MARC-145 cells. a Cell apoptosis was analyzed using annexin V/PI staining. MARC-145 cells were infected with 1 MOI PRRSV, and the apoptotic cells at 12, 24, 36, and 48 h post-infection were analyzed using Alexa Fluor® 488 annexin V/Dead cell apoptosis kit and flow cytometry. b Histogram represents the percentage of early and late apoptotic cells. Statistical anlysis is performed with GrapPad Prism version 6(GrapPad Software, Inc. Fay Avenue, CA, USA) using one-way analysis of variance(one-way ANOVA) followed by Turkey: compare all pairs of column. * indicates p < 0.05, ** indicates p < 0.01, and *** indicates p < 0.001. The following statistical method and differential representation method are the same

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