| |
Baseline
|
1 year
|
2 years
|
3 years
|
4 years
|
5 years
|
|---|
|
(n = 704)
|
(n = 638)
|
(n = 587)
|
(n = 530)
|
(n = 485)
|
(n = 445)
|
|---|
|
ALT (U/L)
|
51 ± 28
|
47 ± 19
|
55 ± 31
|
52 ± 21
|
58 ± 20
|
55 ± 18
|
|
T-BIL (μmol/L)
|
29.2 ± 19.7
|
34.8 ± 20.1
|
32.9 ± 21.8
|
35.9 ± 20.8
|
34.6 ± 19.7
|
27.6 ± 18.0
|
|
Albumin (g/L)
|
28.9 ± 10.2
|
29.1 ± 11.7
|
30.0 ± 9.8
|
28.7 ± 8.2
|
29.7 ± 9.2
|
30.1 ± 12.8
|
|
Blood ammonia (μmol/L)
|
64.7 ± 25.9
|
87.6 ± 27.1 ##
|
81.5 ± 19.8 ##
|
76.2 ± 20.5 ##
|
78.2 ± 21.2 #
|
71.0 ± 11.6
|
|
PTA (%)
|
56.8 ± 12.5
|
37.8 ± 9.1 #
|
51.4 ± 8.7
|
49.2 ± 11.0
|
50.1 ± 10.2
|
50.8 ± 8.9
|
|
INR
|
1.36 ± 0.23
|
1.90 ± 0.46 #
|
1.48 ± 0.51
|
1.50 ± 0.49
|
1.50 ± 0.44
|
1.47 ± 0.38
|
|
Stiffness (KPa)
|
18.6 ± 10.7
|
17.6 ± 9.8
|
17.9 ± 12.7
|
16.8 ± 8.6
|
16.7 ± 9.1
|
17.1 ± 10.2
|
- #P < 0.05, ## P < 0.01 compared with baseline, Dunn’s multiple comparison test
