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Table 3 Virus receptor binding specificity of the avian H6N1, avian H9N2 and human H1N1 influenza viruses

From: Isolation and characterization of novel reassortant H6N1 avian influenza viruses from chickens in Eastern China

Virus

HA titers with normal chicken RBCs

HA titers with α-2,3 specific-neuraminidase-treated chicken RBCs

HA titers with sheep RBCs

Receptor specificity

ZJ-1664(H6N1)

256

32

256

α2,3-SA and α2,6-SA binding

ZJ-1667(H6N1)

256

32

256

α2,3-SA and α2,6-SA binding

A/chicken/Zhejiang/329/2011(H9N2)

256

< 2

256

α2,3-SA binding

A/Puerto Rico/8/1934(H1N1)

256

256

< 2

α2,6-SA binding

  1. Note: The HA titer was defined as the reciprocal of the highest virus dilution resulting in the hemagglutination of RBCs. “α2,3-SA” and “α2,6-SA” indicate “α-2,3-linked sialic acids” (avian receptor) and “α-2,6-linked sialic acids” (human receptor), respectively