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Table 3 Selection pressure analysis of the ORF (3391 codons) of DENV-2 using MEME, SLAC, FEL and IFEL

From: Full-length genome and molecular characterization of dengue virus serotype 2 isolated from an imported patient from Myanmar

AAa position (ORF)

MEME

SLAC

FEL

IFEL

ω

p-Value

ω

p-Value

ω

p-Value

ω

p-Value

prM

 248

55.584

0.062

4.778

0.445

1.525

0.277

1.123

0.278

 253

> 100

0.089

2.368

0.672

0.789

0.446

< 0

1

Envelope

 408

> 100

0.093

2.309

0.712

0.824

0.406

2.171

0.333

 735

> 100

0.096

1.602

0.995

0.486

9.56

< 0

1

NS1

 986

> 100

0.054

2.417

0.68

0.826

0.322

< 0

1

 1010

> 100

0.017

2.431

0.664

0.713

0.416

2.098

0.305

NS2A

 1142

> 100

< 0.001

3.231

0.988

0.997

0.929

< 0

1

 1195

> 100

0.093

1.685

0.946

0.576

0.819

< 0

1

NS2B

 1439

> 100

0.019

4.765

0.447

1.485

0.246

< 0

1

 1459

> 100

0.014

5146

0.8

1.81

0.649

1.044

0.718

NS3

 1489

> 100

0.067

9.674

0.198

3.111

0.979

< 0

1

NS4B

2262

5.444

0.0838

13.16

0.108

3.4

0.088

6.196

0.082

NS5

3310

2.249

0.107

8.065

0.296

4.012

0.085

8.109

0.058

  1. Note: Criteria to determine codons with important evidence of positive selection: p-value < 0.1 in MEME, SLAC, FEL and IFEL. Codons that are detected positive by at least three approaches are listed in the table. Codons with important evidence of positive selection by at least two approaches are marked in bold font
  2. aAA amino acid