Table 1 Comparison of the clinical characteristics of the different groups of HAdV infection
HAdV, N(%) | ||||||
|---|---|---|---|---|---|---|
Positive (n = 174) | Negative (n = 1139) | P | Single Detection (n = 70)a | Co-detection (n = 104)b | P | |
Gender(male) | 111(63.79) | 713(62.60) | 0.98 | 39(55.71) | 68(65.38) | 0.199 |
age (months) IQR | 12.5(10–28.25) | 11(5.98–25) | 0.38 | 14(11–34.5) | 12(8.25–24) | 0.063 |
Age group | ||||||
< 6 | 19(10.92) | 284(24.93) | 0.000 | 5(7.14) | 14(13.46) | 0.190 |
6–23 | 97(55.75) | 521(45.74) | 0.017 | 37(52.86) | 60(57.69) | 0.529 |
24–60 | 46(26.44) | 239(20.98) | 0.104 | 21(30.00) | 25(24.04) | 0.382 |
> 60 | 12(6.90) | 95(8.34) | 0.517 | 7(10.00) | 5(4.81) | 0.228 |
Duration of Hospitalization (days) | 8(6–10) | 7(6–9) | 0.046 | 8(6–10) | 8(6–10) | 0.697 |
Duration of fever (days) | 6(3.5–8) | 4(2–6) | 0.000 | 6(4.5–8) | 5(3–7.75) | 0.202 |
Cough | 174(100) | 1139(100) | 70(100) | 104(100) | ||
Fever | 143(79.89) | 693(60.84) | 0.000 | 61(87.14) | 80(76.92) | 0.092 |
Diarrhea | 33(18.97) | 219(19.22) | 0.935 | 13(18.57) | 20(19.23) | 0.913 |
Wheezing | 73(41.95) | 561(49.25) | 0.073 | 24(34.29) | 49(47.12) | 0.093 |
Vomiting | 30(17.24) | 184(16.15) | 0.718 | 11(15.71) | 19(18.27) | 0.662 |
Outcome | ||||||
Disease severity of CPA | ||||||
Mild | 108(62.07) | 936(82.18) | 0.000 | 38(54.29) | 70(67.31) | 0.083 |
Severe | 33(18.97) | 145(12.73) | 0.025 | 14(20.00) | 19(18.27) | 0.775 |
Very severe | 33(18.97) | 58(5.09) | 0.000 | 18(25.71) | 15(14.42) | 0.062 |
Admission to PICU | 31(17.80) | 89(7.80) | 0.000 | 8(11.40) | 23(22.10) | 0.071 |
supplemental oxygen requirement | 35(20.10) | 134(11.76) | 0.002 | 13(18.57) | 22(21.20) | 0.877 |
HAdV load from NPAs(log 10 copies/mL) | 3.27 ± 2.15 | N | 3.48 ± 2.44 | 3.21 ± 2.02 | 0.408 | |