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Table 1 Comparison of the clinical characteristics of the different groups of HAdV infection

From: Human adenovirus load in respiratory tract secretions are predictors for disease severity in children with human adenovirus pneumonia

  HAdV, N(%)
Positive (n = 174) Negative (n = 1139) P Single Detection
(n = 70)a
Co-detection
(n = 104)b
P
Gender(male) 111(63.79) 713(62.60) 0.98 39(55.71) 68(65.38) 0.199
age (months) IQR 12.5(10–28.25) 11(5.98–25) 0.38 14(11–34.5) 12(8.25–24) 0.063
Age group
 < 6 19(10.92) 284(24.93) 0.000 5(7.14) 14(13.46) 0.190
 6–23 97(55.75) 521(45.74) 0.017 37(52.86) 60(57.69) 0.529
 24–60 46(26.44) 239(20.98) 0.104 21(30.00) 25(24.04) 0.382
 > 60 12(6.90) 95(8.34) 0.517 7(10.00) 5(4.81) 0.228
Duration of Hospitalization (days) 8(6–10) 7(6–9) 0.046 8(6–10) 8(6–10) 0.697
Duration of fever (days) 6(3.5–8) 4(2–6) 0.000 6(4.5–8) 5(3–7.75) 0.202
 Cough 174(100) 1139(100)   70(100) 104(100)  
 Fever 143(79.89) 693(60.84) 0.000 61(87.14) 80(76.92) 0.092
 Diarrhea 33(18.97) 219(19.22) 0.935 13(18.57) 20(19.23) 0.913
 Wheezing 73(41.95) 561(49.25) 0.073 24(34.29) 49(47.12) 0.093
 Vomiting 30(17.24) 184(16.15) 0.718 11(15.71) 19(18.27) 0.662
Outcome
Disease severity of CPA
 Mild 108(62.07) 936(82.18) 0.000 38(54.29) 70(67.31) 0.083
 Severe 33(18.97) 145(12.73) 0.025 14(20.00) 19(18.27) 0.775
 Very severe 33(18.97) 58(5.09) 0.000 18(25.71) 15(14.42) 0.062
Admission to PICU 31(17.80) 89(7.80) 0.000 8(11.40) 23(22.10) 0.071
supplemental oxygen requirement 35(20.10) 134(11.76) 0.002 13(18.57) 22(21.20) 0.877
HAdV load from NPAs(log 10 copies/mL) 3.27 ± 2.15 N   3.48 ± 2.44 3.21 ± 2.02 0.408
  1. aSeventy patients with single HAdV infection, and mycoplasma, chlamydia, and bacteria were not excluded
  2. bOne hundred and four patients with HAdV pathogen plus any other respiratory viral pathogen infection, and mycoplasma, chlamydia, and bacteria were not excluded