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Fig. 4 | Virology Journal

Fig. 4

From: Experimental infection of mice with noncytopathic bovine viral diarrhea virus 2 increases the number of megakaryocytes in bone marrow

Fig. 4

Histopathological features of Peyer’s patches, spleen, and bone marrow on day 5 pi in mice inoculated orally with a low (4 × 105 TCID50) of ncp BVDV-2 or in mice with the mock infection. Lympholysis was observed in Peyer’s patches (a) and spleen (c, blue arrow). Monocytes infiltrated the red pulp, and the number of megakaryocytes increased in the spleen (c, black arrow), and in bone marrow (e), respectively. No histological changes were observed in Peyer’s patches (b), spleen (d), and bone marrow (f) of mock-infected mice. Magnification in all images: ×200. All the experiments were repeated three times

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