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Table 1 Cytotoxicity and antiviral activity of quercetin against enterovirus 71 (EV71)

From: Inhibition of enterovirus 71 replication and viral 3C protease by quercetin

Cell types Quercetin Ribarivina
EC50b (μM) CC50c (μM) SId EC50 (μM) CC50 (μM) SI
RD 12.1e±3.6 >200 >16.6 34.5±3.1 >200 >5.8
Vero 8.8±2.2 >200 >22.8 42.8±6.8 >200 >4.7
  1. aRibavirin, used as a positive control
  2. bEC50: compound concentration required to achieve 50% protection from virus-induced cytopathogenicity
  3. cCC50: compound concentration required to reduce cell viability by 50%
  4. dSI (selectivity index): ratio by CC50/EC50
  5. eValues represent the mean ± SD of three independent experiments